About the Authors

Helene Skjøt-Arkil

Affiliations Nordic Bioscience A/S, Herlev, Denmark, School of Endocrinology, University of Southern Denmark, Odense, Denmark

Rikke E. Clausen

Affiliation Nordic Bioscience A/S, Herlev, Denmark

Lars M. Rasmussen

Affiliation Institute of Clinical Research, Odense University Hospital, Odense, Denmark

Wanchun Wang

Affiliation Nordic Bioscience Beijing, Beijing, China

Yaguo Wang

Affiliation Nordic Bioscience Beijing, Beijing, China

Qinlong Zheng

Affiliation Nordic Bioscience Beijing, Beijing, China

Hans Mickley

Affiliation Department of Cardiology, Odense University Hospital, Odense, Denmark

Lotte Saaby

Affiliation Department of Cardiology, Odense University Hospital, Odense, Denmark

Axel C. P. Diederichsen

Affiliation Department of Cardiology, Odense University Hospital, Odense, Denmark

Jess Lambrechtsen

Affiliation Department of Cardiology, Svenborg Hospital, Svenborg, Denmark

Fernando J. Martinez

Affiliation Division of Pulmonary and Critical Care Medicine and Department of Pathology, University of Michigan, Ann Arbor, Michigan, United States of America

Cory M. Hogaboam

Affiliation Division of Pulmonary and Critical Care Medicine and Department of Pathology, University of Michigan, Ann Arbor, Michigan, United States of America

MeiLan Han

Affiliation Division of Pulmonary and Critical Care Medicine and Department of Pathology, University of Michigan, Ann Arbor, Michigan, United States of America

Martin R. Larsen

Affiliation Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark

Arkadiusz Nawrocki

Affiliation Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark

Ben Vainer

Affiliation Department of Pathology, Rigshopitalet, University of Copenhagen, Copenhagen, Denmark

Dorrit Krustrup

Affiliation Department of Pathology, Rigshopitalet, University of Copenhagen, Copenhagen, Denmark

Marina Bjørling-Poulsen

Affiliation Institute of Clinical Research, Odense University Hospital, Odense, Denmark

Morten A. Karsdal

Affiliation Nordic Bioscience A/S, Herlev, Denmark

Diana J. Leeming

DJL@nordicbioscience.com

Affiliation Nordic Bioscience A/S, Herlev, Denmark

Competing Interests

HSA, WW, YW, QZ, MAK and DJL are full-time employees of Nordic Bioscience. MAK holds stock in Nordic Bioscience. Other authors have no competing interests. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: HSA REC MAK DJL. Performed the experiments: HSA REC. Analyzed the data: HSA REC LMR DJL MAK. Contributed reagents/materials/analysis tools: MRL AN WW YW QZ LMR MBP BV DK LS HM JL ACPD FJM CMH MH. Wrote the paper: HAS REC DJL MAK LMR.