About the Authors

Modesto J. Remuiñán

Modesto.b.remuinan@gsk.com

Affiliation Diseases of the Developing World, GlaxoSmithKline, Tres Cantos, Madrid, Spain

Esther Pérez-Herrán

Affiliation Diseases of the Developing World, GlaxoSmithKline, Tres Cantos, Madrid, Spain

Joaquín Rullás

Affiliation Diseases of the Developing World, GlaxoSmithKline, Tres Cantos, Madrid, Spain

Carlos Alemparte

Affiliation Diseases of the Developing World, GlaxoSmithKline, Tres Cantos, Madrid, Spain

María Martínez-Hoyos

Affiliation Diseases of the Developing World, GlaxoSmithKline, Tres Cantos, Madrid, Spain

David J. Dow

Affiliation Molecular and Cellular Technologies, GlaxoSmithKline, Stevenage, United Kingdom

Johnson Afari

Affiliation Molecular and Cellular Technologies, GlaxoSmithKline, Stevenage, United Kingdom

Nalini Mehta

Affiliation Molecular and Cellular Technologies, GlaxoSmithKline, Stevenage, United Kingdom

Jorge Esquivias

Affiliation Diseases of the Developing World, GlaxoSmithKline, Tres Cantos, Madrid, Spain

Elena Jiménez

Affiliation Diseases of the Developing World, GlaxoSmithKline, Tres Cantos, Madrid, Spain

Fátima Ortega-Muro

Affiliation Diseases of the Developing World, GlaxoSmithKline, Tres Cantos, Madrid, Spain

María Teresa Fraile-Gabaldón

Affiliation Diseases of the Developing World, GlaxoSmithKline, Tres Cantos, Madrid, Spain

Vickey L. Spivey

Affiliation Molecular and Cellular Technologies, GlaxoSmithKline, Stevenage, United Kingdom

Nicholas J. Loman

Affiliation School of Biosciences, University of Birmingham, Edgbaston, United Kingdom

Mark J. Pallen

Affiliation School of Biosciences, University of Birmingham, Edgbaston, United Kingdom

Chrystala Constantinidou

Affiliation School of Biosciences, University of Birmingham, Edgbaston, United Kingdom

Douglas J. Minick

Affiliation Department of Analytical Chemistry, GlaxoSmithKline, Research Triangle Park, North Carolina, United States of America

Mónica Cacho

Affiliation Diseases of the Developing World, GlaxoSmithKline, Tres Cantos, Madrid, Spain

María José Rebollo-López

Affiliation Diseases of the Developing World, GlaxoSmithKline, Tres Cantos, Madrid, Spain

Carolina González

Affiliation Diseases of the Developing World, GlaxoSmithKline, Tres Cantos, Madrid, Spain

Verónica Sousa

Affiliation Diseases of the Developing World, GlaxoSmithKline, Tres Cantos, Madrid, Spain

Iñigo Angulo-Barturen

Affiliation Diseases of the Developing World, GlaxoSmithKline, Tres Cantos, Madrid, Spain

Alfonso Mendoza-Losana

Affiliation Diseases of the Developing World, GlaxoSmithKline, Tres Cantos, Madrid, Spain

David Barros

Affiliation Diseases of the Developing World, GlaxoSmithKline, Tres Cantos, Madrid, Spain

Gurdyal S. Besra

Affiliation School of Biosciences, University of Birmingham, Edgbaston, United Kingdom

Lluís Ballell

Affiliation Diseases of the Developing World, GlaxoSmithKline, Tres Cantos, Madrid, Spain

Nicholas Cammack

Affiliation Diseases of the Developing World, GlaxoSmithKline, Tres Cantos, Madrid, Spain

Competing Interests

The authors declare the following co-authors Modesto J. Remuiñán, Esther Pérez-Herrán, Joaquín Rullás, Carlos Alemparte, Maria Martinez-Hoyos, David J. Dow, Johnson Afari, Nalini Mehta, Jorge Esquivias, Elena Jiménez, Fátima Ortega-Muro, María Teresa Fraile-Gabaldón, Vickey L. Spivey, Douglas J. Minick, Mónica Cacho, María Jose Rebollo-Lopez, Carolina Gonzalez, Verónica Sousa, Iñigo Angulo- Barturen, Alfonso Mendoza-Losana, David Barros, Lluís Ballell and Nicholas Cammack are employed by GlaxoSmithKline. However, this does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials. They also declare there is the following public patent (WO2012143522, Tetrahydropyrazolo [1,5-A] pyrimidine as anti-tuberculosis compounds, 20 April 2012) relating to material pertinent to this article. There are no further patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: MJR EPH JR CA DJD EJ FOM MTFG IAB AML DB GSB LB NC. Performed the experiments: EPH JR CA MMH JA NM JE DJM MC MJRL CG VS. Analyzed the data: EPH JR JA NM FOM VLS NJL MJP CC DJM. Contributed reagents/materials/analysis tools: MC JE. Wrote the paper: MJR GSB LB.