About the Authors

Futoshi Nakagami

Contributed equally to this work with: Futoshi Nakagami, Hiroshi Koriyama

Affiliations Department of Clinical Gene Therapy, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan, Department of Geriatric Medicine, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan

Hiroshi Koriyama

Contributed equally to this work with: Futoshi Nakagami, Hiroshi Koriyama

Affiliations Department of Clinical Gene Therapy, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan, Department of Geriatric Medicine, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan

Hironori Nakagami

morishita@cgt.med.osaka-u.ac.jp (RM); nakagami@gts.med.osaka-u.ac.jp (HN)

Affiliation Division of Vascular Medicine and Epigenetics, United Graduate School of Child Development, Osaka University, Suita, Osaka, Japan

Mariana Kiomy Osako

Affiliations Department of Clinical Gene Therapy, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan, Department of Geriatric Medicine, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan

Munehisa Shimamura

Affiliation Division of Vascular Medicine and Epigenetics, United Graduate School of Child Development, Osaka University, Suita, Osaka, Japan

Mariko Kyutoku

Affiliation Department of Clinical Gene Therapy, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan

Takashi Miyake

Affiliation Division of Vascular Medicine and Epigenetics, United Graduate School of Child Development, Osaka University, Suita, Osaka, Japan

Tomohiro Katsuya

Affiliation Department of Clinical Gene Therapy, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan

Hiromi Rakugi

Affiliation Department of Geriatric Medicine, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan

Ryuichi Morishita

morishita@cgt.med.osaka-u.ac.jp (RM); nakagami@gts.med.osaka-u.ac.jp (HN)

Affiliation Department of Clinical Gene Therapy, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan

Competing Interests

Prof. Ryuichi Morishita is a PLOS ONE Editorial Board Member. However, this does not alter the authors' adherence to all the PLOS ONE politics on sharing data and materials.

Author Contributions

Conceived and designed the experiments: FN HN RM. Performed the experiments: FN HN HK MKO MK. Analyzed the data: FN HN MS TM TK. Contributed reagents/materials/analysis tools: TK HR. Wrote the paper: FN HN RM.