About the Authors

Yidong Wang

Affiliations State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan, China, Department of Genetics, Albert Einstein College of Medicine, Bronx, New York, United States of America

Bingruo Wu

Affiliation Department of Genetics, Albert Einstein College of Medicine, Bronx, New York, United States of America

Alyssa A. Chamberlain

Affiliation Department of Genetics, Albert Einstein College of Medicine, Bronx, New York, United States of America

Wendy Lui

Affiliation Department of Genetics, Albert Einstein College of Medicine, Bronx, New York, United States of America

Pratistha Koirala

Affiliation Department of Genetics, Albert Einstein College of Medicine, Bronx, New York, United States of America

Katalin Susztak

Affiliation Renal, Electrolyte and Hypertension Division, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Diana Klein

Affiliation Institute of Anatomy, University Hospital Essen, Essen, North Rhine-Westphalia, Germany

Verdon Taylor

Affiliation Department of Biomedicine, University of Basel, Basel, Switzerland

Bin Zhou

bin.zhou@einstein.yu.edu

Affiliations Department of Genetics, Albert Einstein College of Medicine, Bronx, New York, United States of America, Departments of Pediatrics and Medicine (Cardiology), The Wilf Family Cardiovascular Research Institute, Albert Einstein College of Medicine, Bronx, New York, United States of America, Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University and Jiangsu Province Hospital, Nanjing, Jiangsu, China

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Designed and generated the Nfatc1-Cre mouse line: BW BZ. Obtained permission for use of floxed Jagged1 conditional mouse line: VT. Obtained permission for use of Wnt2 cell line: DK. Conceived and designed the experiments: YW BW BZ. Performed the experiments: YW BW BZ. Analyzed the data: YW BW AAC WL PK BZ. Contributed reagents/materials/analysis tools: YW BW KS DK VT BZ. Wrote the paper: YW BZ.