About the Authors

Lynn A. Beer

Affiliation Center for Systems and Computational Biology, and Molecular and Cellular Oncogenesis Program, The Wistar Institute, Philadelphia, Pennsylvania, United States of America

Huan Wang

Affiliation Center for Systems and Computational Biology, and Molecular and Cellular Oncogenesis Program, The Wistar Institute, Philadelphia, Pennsylvania, United States of America

Hsin-Yao Tang

Affiliation Center for Systems and Computational Biology, and Molecular and Cellular Oncogenesis Program, The Wistar Institute, Philadelphia, Pennsylvania, United States of America

Zhijun Cao

Current address: The National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, Arizona, United States of America

Affiliation Center for Systems and Computational Biology, and Molecular and Cellular Oncogenesis Program, The Wistar Institute, Philadelphia, Pennsylvania, United States of America

Tony Chang-Wong

Affiliation Center for Systems and Computational Biology, and Molecular and Cellular Oncogenesis Program, The Wistar Institute, Philadelphia, Pennsylvania, United States of America

Janos L. Tanyi

Affiliation Ovarian Cancer Research Center, The University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Rugang Zhang

Affiliation Gene Expression and Regulation Program, The Wistar Institute, Philadelphia, Pennsylvania, United States of America

Qin Liu

Affiliation Center for Systems and Computational Biology, and Molecular and Cellular Oncogenesis Program, The Wistar Institute, Philadelphia, Pennsylvania, United States of America

David W. Speicher

speicher@wistar.org

Affiliation Center for Systems and Computational Biology, and Molecular and Cellular Oncogenesis Program, The Wistar Institute, Philadelphia, Pennsylvania, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Advice and critical evaluation of manuscript: RZ. Conceived and designed the experiments: LAB HYT DWS. Performed the experiments: LAB HW HYT ZC TCW. Analyzed the data: LAB HYT ZC QL DWS. Contributed reagents/materials/analysis tools: JLT. Wrote the paper: LAB HYT DWS.