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Research Article

Prenatal Ethanol Exposure Causes Glucose Intolerance with Increased Hepatic Gluconeogenesis and Histone Deacetylases in Adult Rat Offspring: Reversal by Tauroursodeoxycholic Acid

  • Xing-Hai Yao,

    Affiliation: Department of Internal Medicine, University of Manitoba, Winnipeg, Manitoba, Canada

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  • Hoa K. Nguyen,

    Affiliation: Department of Physiology, University of Manitoba, Winnipeg, Manitoba, Canada

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  • B. L. Grégoire Nyomba mail

    bnyomba@cc.umanitoba.ca

    Affiliation: Department of Internal Medicine, University of Manitoba, Winnipeg, Manitoba, Canada

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  • Published: March 27, 2013
  • DOI: 10.1371/journal.pone.0059680

About the Authors

Xing-Hai Yao, B. L. Grégoire Nyomba
Department of Internal Medicine, University of Manitoba, Winnipeg, Manitoba, Canada
Hoa K. Nguyen
Department of Physiology, University of Manitoba, Winnipeg, Manitoba, Canada

Corresponding Author

Email: bnyomba@cc.umanitoba.ca

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Manuscript revision and approval: BLN HKN XHY. Conceived and designed the experiments: BLN XHY. Performed the experiments: XHY HKN. Analyzed the data: XHY BLN. Contributed reagents/materials/analysis tools: BLN. Wrote the paper: XHY BLN.