About the Authors

Delia Bethell

delia.bethell@afrims.org

Affiliation Department of Immunology and Medicine, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand

David Saunders

Affiliation Department of Immunology and Medicine, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand

Anan Jongkaewwattana

Affiliation Virology and Cell Technology Laboratory, National Center for Genetic Engineering and Biotechnology, Bangkok, Thailand

Jarin Kramyu

Affiliation Virology and Cell Technology Laboratory, National Center for Genetic Engineering and Biotechnology, Bangkok, Thailand

Arunee Thitithayanont

Affiliation Faculty of Science, Mahidol University, Bangkok, Thailand

Suwimon Wiboon-ut

Affiliation Faculty of Science, Mahidol University, Bangkok, Thailand

Kosol Yongvanitchit

Affiliation Department of Immunology and Medicine, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand

Amporn Limsalakpetch

Affiliation Department of Immunology and Medicine, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand

Utaiwan Kum-Arb

Affiliation Department of Immunology and Medicine, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand

Nichapat Uthaimongkol

Affiliation Department of Immunology and Medicine, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand

Jean Michel Garcia

Affiliation University of Hong Kong-Pasteur Research Center, Hong Kong Special Administrative Region, China

Ans E. Timmermans

Affiliation Department of Immunology and Medicine, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand

Malik Peiris

Affiliation University of Hong Kong-Pasteur Research Center, Hong Kong Special Administrative Region, China

Stephen Thomas

Affiliation Department of Virology, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand

Anneke Engering

Affiliation Department of Immunology and Medicine, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand

Richard G. Jarman

Affiliation Department of Virology, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand

Duangrat Mongkolsirichaikul

Affiliation Department of Virology, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand

Carl Mason

Affiliation Department of Enteric Diseases, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand

Nuanpan Khemnu

Affiliation Department of Enteric Diseases, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand

Stuart D. Tyner

Affiliation Department of Immunology and Medicine, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand

Mark M. Fukuda

Affiliation Department of Immunology and Medicine, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand

Douglas S. Walsh

Affiliation Department of Immunology and Medicine, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand

Sathit Pichyangkul

Affiliation Department of Immunology and Medicine, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand

Competing Interests

The authors declare they have no competing interests. This study was supported by MedImmune, which also provided FluMist Seasonal Trivalent Live Attenuated Intranasal Vaccine for use in the trial. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors. There are no patents, products in development or marketed products to declare.

Author Contributions

Conceived and designed the experiments: DB DS AE SDT MF SP. Performed the experiments: DB DS AJ JK AT SW KY AL UK NU JMG AT MP ST RGJ DM NK SDT DSW SP. Analyzed the data: DB DS KY AL NU MMF DSW SP. Contributed reagents/materials/analysis tools: AJ JK AT SW JMG MP CM. Wrote the paper: DB DS AT JMG AT ST AE RGJ SDT MMF DSW SP.