About the Authors

Adewole Adamson

Affiliations Molecular Immunology and Inflammation Branch, National Institute of Arthritis, Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland, United States of America, Harvard-Massachusetts Institute of Technology Division of Health, Sciences and Technology, Boston, Massachusetts, United States of America

Kamran Ghoreschi

Affiliations Molecular Immunology and Inflammation Branch, National Institute of Arthritis, Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland, United States of America, Department of Dermatology, University Medical Center, Eberhard Karls University, Tübingen, Germany

Matthew Rittler

Affiliation Radiation Oncology Branch, National Cancer Institute, Bethesda, Maryland, United States of America

Qian Chen

Affiliation Division of Gastroenterology, Department of Internal Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China

Hong-Wei Sun

Affiliation Molecular Immunology and Inflammation Branch, National Institute of Arthritis, Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

Golnaz Vahedi

Affiliation Molecular Immunology and Inflammation Branch, National Institute of Arthritis, Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

Yuka Kanno

Affiliation Molecular Immunology and Inflammation Branch, National Institute of Arthritis, Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

William G. Stetler-Stevenson

Affiliation Radiation Oncology Branch, National Cancer Institute, Bethesda, Maryland, United States of America

John J. O’Shea

Affiliation Molecular Immunology and Inflammation Branch, National Institute of Arthritis, Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

Arian Laurence

laurencea@mail.nih.gov

Affiliation Molecular Immunology and Inflammation Branch, National Institute of Arthritis, Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

Competing Interests

The authors acknowledge that AA was supported by the National Institutes of Health Clinical Research Training Program, a public-private partnership between the Foundation for the National Institutes of Health and Pfizer Inc. Furthermore, there are no patents, products in development or marketed products that are associated with the findings or conclusions made in the manuscript. The authors will adhere to the PLOS ONE policies on sharing data and materials mentioned in the manuscript.

Author Contributions

Conceived and designed the experiments: AA AL JJO WGS-S YK KG MR. Performed the experiments: AA AL KG MR QC YK. Analyzed the data: H-WS GV YK. Wrote the paper: AL JJO.