About the Authors

Michael C. Rowbotham

rowbotm@cpmcri.org

Affiliation California Pacific Medical Center Research Institute, San Francisco, California, United States of America

John Astin

Affiliation California Pacific Medical Center Research Institute, San Francisco, California, United States of America

Kaitlin Greene

Affiliation California Pacific Medical Center Research Institute, San Francisco, California, United States of America

Steven R. Cummings

Affiliations California Pacific Medical Center Research Institute, San Francisco, California, United States of America, San Francisco Coordinating Center, San Francisco, California, United States of America

Competing Interests

MCR, JA, and KG have no conflict of interest with reference to Mytrus, the maker of the interactive iPad device. The study was funded by departmental funds at CPMCRI under the control of MCR. SRC is a founder and officer of Mytrus but was not involved in any contact with subjects or statistical analysis. JA was responsible for final data analysis. Declaration of competing interests for author SRC because of his relationship to Mytrus. SRC is Chief Scientific Officer and Board Chairman at Mytrus. The study was not funded by Mytrus. No other author has any relationship to Mytrus. No other author has a competing interest to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: MCR JA SRC. Performed the experiments: MCR KG JA. Analyzed the data: MCR JA. Wrote the paper: MCR JA KG SRC.