About the Authors

Richard W. Ahn

Contributed equally to this work with: Richard W. Ahn, Susan L. Barrett

Affiliations Department of Chemistry, Chemistry of Life Processes Institute, Northwestern University, Evanston, Illinois, United States of America, Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, Illinois, United States of America, Member of the Oncofertility Consortium, Northwestern University, Chicago, Illinois, United States of America

Susan L. Barrett

Contributed equally to this work with: Richard W. Ahn, Susan L. Barrett

Affiliations Member of the Oncofertility Consortium, Northwestern University, Chicago, Illinois, United States of America, Department of Obstetrics and Gynecology, Northwestern University, Chicago, Illinois, United States of America, Center for Reproductive Science Reproductive Biology Training Program, Northwestern University, Evanston, Illinois, United States of America

Meera R. Raja

Affiliation Department of Chemistry, Chemistry of Life Processes Institute, Northwestern University, Evanston, Illinois, United States of America

Jennifer K. Jozefik

Affiliations Member of the Oncofertility Consortium, Northwestern University, Chicago, Illinois, United States of America, Department of Obstetrics and Gynecology, Northwestern University, Chicago, Illinois, United States of America

Lidia Spaho

Affiliations Member of the Oncofertility Consortium, Northwestern University, Chicago, Illinois, United States of America, Department of Obstetrics and Gynecology, Northwestern University, Chicago, Illinois, United States of America

Haimei Chen

Affiliations Department of Chemistry, Chemistry of Life Processes Institute, Northwestern University, Evanston, Illinois, United States of America, Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, Illinois, United States of America, Member of the Oncofertility Consortium, Northwestern University, Chicago, Illinois, United States of America

Marcel B. Bally

Affiliations Centre for Drug Research and Development, University of British Columbia, Vancouver, British Columbia, Canada, Department of Advanced Therapeutics, BC Cancer Agency, British Columbia, Canada

Andrew P. Mazar

Affiliations Department of Chemistry, Chemistry of Life Processes Institute, Northwestern University, Evanston, Illinois, United States of America, Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, Illinois, United States of America

Michael J. Avram

Affiliations Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, Illinois, United States of America, Department of Anesthesiology and Mary Beth Donnelley Clinical Pharmacology Core Facility of the Robert H. Lurie Comprehensive Cancer Center of the Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America

Jane N. Winter

Affiliations Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, Illinois, United States of America, Department of Medicine, Division of Hematology/Oncology and Lymphoma Program, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America

Leo I. Gordon

Affiliations Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, Illinois, United States of America, Department of Medicine, Division of Hematology/Oncology and Lymphoma Program, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America

Lonnie D. Shea

Affiliations Member of the Oncofertility Consortium, Northwestern University, Chicago, Illinois, United States of America, Department of Chemical and Biological Engineering, Northwestern University, Evanston, Illinois, United States of America

Thomas V. O’Halloran

t-ohalloran@northwestern.edu (TVO); tkw@northwestern.edu (TKW)

Affiliations Department of Chemistry, Chemistry of Life Processes Institute, Northwestern University, Evanston, Illinois, United States of America, Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, Illinois, United States of America, Member of the Oncofertility Consortium, Northwestern University, Chicago, Illinois, United States of America

Teresa K. Woodruff

t-ohalloran@northwestern.edu (TVO); tkw@northwestern.edu (TKW)

Affiliations Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, Illinois, United States of America, Member of the Oncofertility Consortium, Northwestern University, Chicago, Illinois, United States of America, Department of Obstetrics and Gynecology, Northwestern University, Chicago, Illinois, United States of America

Competing Interests

TVO and HC are inventors on a patent issued to Northwestern University which covers the NB(Ni,As). This agent is not currently in development and the patent does not alter the authors’ ability to adhere to all PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: RWA SLB MRR JKJ LS HC MBB APM MJA JNW LIG LDS TVO TKW. Performed the experiments: RWA SLB MRR JKJ HC LS. Analyzed the data: RWA SLB MRR JKJ LS HC MBB APM MJA JNW LIG LDS TVO TKW. Contributed reagents/materials/analysis tools: MBB APM MJA JNW LIG LDS TVO TKW. Wrote the paper: RWA SLB TVO TKW.