About the Authors

Calpurnia Jayakumar

Affiliation Department of Medicine and Vascular Biology Center, Georgia Health Sciences University, Augusta, Georgia, United States of America

Punithavathi Ranganathan

Affiliation Department of Medicine and Vascular Biology Center, Georgia Health Sciences University, Augusta, Georgia, United States of America

Prasad Devarajan

Affiliation Department of Nephrology and Hypertension, Cincinnati Children’s Hospital Medical Center, University of Cincinnati School of Medicine, Cincinnati, Ohio, United States of America

Catherine D. Krawczeski

Affiliation Heart Institute, Cincinnati Children’s Hospital Medical Center, University of Cincinnati School of Medicine, Cincinnati, Ohio, United States of America

Stephen Looney

Affiliation Department of Biostatistics, Georgia Health Sciences University, Augusta, Georgia, United States of America

Ganesan Ramesh

gramesh@georgiahealth.edu

Affiliation Department of Medicine and Vascular Biology Center, Georgia Health Sciences University, Augusta, Georgia, United States of America

Competing Interests

The authors have the following interests. Dr. Ramesh and Georgia Health Sciences University have submitted a provisional patent application for the use of urine semaphorin 3A for the early diagnosis of AKI. Dr. Devarajan is a co-inventor on patents related to NGAL as a biomarker of AKI, and is a consultant to Abbott Diagnostics and Biosite, Inc. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: GR. Performed the experiments: CJ PR GR. Analyzed the data: SL PD. Contributed reagents/materials/analysis tools: PD CDK. Wrote the paper: CJ GR PD SL.