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Research Article

Evaluating Genome-Wide Association Study-Identified Breast Cancer Risk Variants in African-American Women

  • Jirong Long mail,

    Jirong.Long@Vanderbilt.Edu

    Affiliation: Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

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  • Ben Zhang,

    Affiliation: Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

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  • Lisa B. Signorello,

    Affiliations: Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America, International Epidemiology Institute, Rockville, Maryland, United States of America

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  • Qiuyin Cai,

    Affiliation: Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

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  • Sandra Deming-Halverson,

    Affiliation: Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

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  • Martha J. Shrubsole,

    Affiliation: Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

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  • Maureen Sanderson,

    Affiliation: Meharry Medical College, Nashville, Tennessee, United States of America

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  • Joe Dennis,

    Affiliation: Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK

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  • Kyriaki Michailiou,

    Affiliation: Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK

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  • Douglas F. Easton,

    Affiliations: Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK, Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK

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  • Xiao-Ou Shu,

    Affiliation: Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

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  • William J. Blot,

    Affiliations: Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America, International Epidemiology Institute, Rockville, Maryland, United States of America

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  • Wei Zheng

    Affiliation: Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

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  • Published: April 08, 2013
  • DOI: 10.1371/journal.pone.0058350

About the Authors

Jirong Long, Ben Zhang, Lisa B. Signorello, Qiuyin Cai, Sandra Deming-Halverson, Martha J. Shrubsole, Xiao-Ou Shu, William J. Blot, Wei Zheng
Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America
Lisa B. Signorello, William J. Blot
International Epidemiology Institute, Rockville, Maryland, United States of America
Maureen Sanderson
Meharry Medical College, Nashville, Tennessee, United States of America
Joe Dennis, Kyriaki Michailiou, Douglas F. Easton
Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK
Douglas F. Easton
Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK

Corresponding Author

Email: Jirong.Long@Vanderbilt.Edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JL WZ. Performed the experiments: QC. Analyzed the data: JL. Contributed reagents/materials/analysis tools: JL LDS QC SDH MJS MS XOS WJB. Wrote the paper: JL.