About the Authors

Paola A. Bignone

Affiliation Mandala Biosciences LLC, San Diego, California, United States of America

Rachel A. Krupa

Affiliation Mandala Biosciences LLC, San Diego, California, United States of America

Hal Sternberg

Affiliation BioTime Inc., Alameda, California, United States of America

Walter D. Funk

Affiliation BioTime Inc., Alameda, California, United States of America

Evan Y. Snyder

Affiliation Sanford-Burnham Medical Research Institute, La Jolla, California, United States of America

Michael D. West

Affiliation BioTime Inc., Alameda, California, United States of America

David Larocca

dlarocca@mandalabio.com

Affiliation Mandala Biosciences LLC, San Diego, California, United States of America

Competing Interests

The authors have the following interests: Paola A. Bignone, Rachel A. Krupa and David Larocca are employed by Mandala Biosciences LLC, and Hal Sternberg, Walter D. Funk and Michael D. West by BioTime Inc. The embryonic progenitor cell lines were developed and obtained from BioTime, Inc. in Alameda, CA. There are no further patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Performed gene expression analysis of W10 cell line: HS. Contributed to the conception and design of the study: WDF EYS MDW. Conceived and designed the experiments: DL. Performed the experiments: PAB RAK. Analyzed the data: PAB RAK. Wrote the paper: PAB DL.