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Research Article

Neuropeptide Y Is Produced by Adipose Tissue Macrophages and Regulates Obesity-Induced Inflammation

  • Kanakadurga Singer,

    Affiliation: Department of Pediatrics and Communicable Diseases, University of Michigan Medical School, Ann Arbor, Michigan, United States of America

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  • David L. Morris,

    Affiliation: Department of Pediatrics and Communicable Diseases, University of Michigan Medical School, Ann Arbor, Michigan, United States of America

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  • Kelsie E. Oatmen,

    Affiliation: Department of Pediatrics and Communicable Diseases, University of Michigan Medical School, Ann Arbor, Michigan, United States of America

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  • Tianyi Wang,

    Affiliation: Department of Pediatrics and Communicable Diseases, University of Michigan Medical School, Ann Arbor, Michigan, United States of America

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  • Jennifer DelProposto,

    Affiliation: Department of Pediatrics and Communicable Diseases, University of Michigan Medical School, Ann Arbor, Michigan, United States of America

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  • Taleen Mergian,

    Affiliation: Department of Pediatrics and Communicable Diseases, University of Michigan Medical School, Ann Arbor, Michigan, United States of America

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  • Kae Won Cho,

    Affiliation: Department of Pediatrics and Communicable Diseases, University of Michigan Medical School, Ann Arbor, Michigan, United States of America

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  • Carey N. Lumeng mail

    clumeng@umich.edu

    Affiliations: Department of Pediatrics and Communicable Diseases, University of Michigan Medical School, Ann Arbor, Michigan, United States of America, Department of Molecular and Integrative Physiology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America

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  • Published: March 05, 2013
  • DOI: 10.1371/journal.pone.0057929

About the Authors

Kanakadurga Singer, David L. Morris, Kelsie E. Oatmen, Tianyi Wang, Jennifer DelProposto, Taleen Mergian, Kae Won Cho, Carey N. Lumeng
Department of Pediatrics and Communicable Diseases, University of Michigan Medical School, Ann Arbor, Michigan, United States of America
Carey N. Lumeng
Department of Molecular and Integrative Physiology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America

Corresponding Author

Email: clumeng@umich.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: CNL KS. Performed the experiments: KS DLM KEO TW JD TM KWC. Analyzed the data: KS CNL. Wrote the paper: KS CNL.