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Research Article

Molecular Profiling of Multiple Human Cancers Defines an Inflammatory Cancer-Associated Molecular Pattern and Uncovers KPNA2 as a Uniform Poor Prognostic Cancer Marker

  • Saleh M. Rachidi,

    Affiliations: Department of Microbiology and Immunology, South Carolina Clinical and Translational Research Institute (SCTR), Medical University of South Carolina, Charleston, South Carolina, United States of America, Hollings Cancer Center, South Carolina Clinical and Translational Research Institute (SCTR), Medical University of South Carolina, Charleston, South Carolina, United States of America

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  • Tingting Qin,

    Affiliation: Division of Bioinformatics, Department of Biochemistry and Molecular Biology, South Carolina Clinical and Translational Research Institute (SCTR), Medical University of South Carolina, Charleston, South Carolina, United States of America

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  • Shaoli Sun,

    Affiliation: Department of Pathology and Laboratory Medicine, South Carolina Clinical and Translational Research Institute (SCTR), Medical University of South Carolina, Charleston, South Carolina, United States of America

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  • W. Jim Zheng,

    Affiliations: Division of Bioinformatics, Department of Biochemistry and Molecular Biology, South Carolina Clinical and Translational Research Institute (SCTR), Medical University of South Carolina, Charleston, South Carolina, United States of America, Computational Biology Core Facility, South Carolina Clinical and Translational Research Institute (SCTR), Medical University of South Carolina, Charleston, South Carolina, United States of America

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  • Zihai Li mail

    zihai@musc.edu

    Affiliations: Department of Microbiology and Immunology, South Carolina Clinical and Translational Research Institute (SCTR), Medical University of South Carolina, Charleston, South Carolina, United States of America, Hollings Cancer Center, South Carolina Clinical and Translational Research Institute (SCTR), Medical University of South Carolina, Charleston, South Carolina, United States of America

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  • Published: March 25, 2013
  • DOI: 10.1371/journal.pone.0057911

About the Authors

Saleh M. Rachidi, Zihai Li
Department of Microbiology and Immunology, South Carolina Clinical and Translational Research Institute (SCTR), Medical University of South Carolina, Charleston, South Carolina, United States of America
Saleh M. Rachidi, Zihai Li
Hollings Cancer Center, South Carolina Clinical and Translational Research Institute (SCTR), Medical University of South Carolina, Charleston, South Carolina, United States of America
Tingting Qin, W. Jim Zheng
Division of Bioinformatics, Department of Biochemistry and Molecular Biology, South Carolina Clinical and Translational Research Institute (SCTR), Medical University of South Carolina, Charleston, South Carolina, United States of America
Shaoli Sun
Department of Pathology and Laboratory Medicine, South Carolina Clinical and Translational Research Institute (SCTR), Medical University of South Carolina, Charleston, South Carolina, United States of America
W. Jim Zheng
Computational Biology Core Facility, South Carolina Clinical and Translational Research Institute (SCTR), Medical University of South Carolina, Charleston, South Carolina, United States of America

Corresponding Author

Email: zihai@musc.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SMR WJZ ZL. Performed the experiments: SMR TQ. Analyzed the data: SMR ZL. Contributed reagents/materials/analysis tools: SS ZL. Wrote the paper: SMR ZL.