Trypanosoma cruzi Coaxes Cardiac Fibroblasts into Preventing Cardiomyocyte Death by Activating Nerve Growth Factor Receptor TrkA

Daniel Aridgides; Ryan Salvador; Mercio PereiraPerrin

doi:10.1371/journal.pone.0057450

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Open Access

Peer-reviewed

Research Article

Trypanosoma cruzi Coaxes Cardiac Fibroblasts into Preventing Cardiomyocyte Death by Activating Nerve Growth Factor Receptor TrkA

Daniel Aridgides,

Affiliations Graduate Program in Immunology, Sackler School of Graduate Biomedical Sciences, Tufts University, Boston, Massachusetts, United States of America,, Department of Pathology, Tufts University School of Medicine, Boston, Massachusetts, United States of America
⨯
Ryan Salvador,

Affiliations Graduate Program in Immunology, Sackler School of Graduate Biomedical Sciences, Tufts University, Boston, Massachusetts, United States of America,, Department of Pathology, Tufts University School of Medicine, Boston, Massachusetts, United States of America
⨯
Mercio PereiraPerrin

* E-mail: Mercio.perrin@tufts.edu

Affiliations Graduate Program in Immunology, Sackler School of Graduate Biomedical Sciences, Tufts University, Boston, Massachusetts, United States of America,, Department of Pathology, Tufts University School of Medicine, Boston, Massachusetts, United States of America
⨯

Trypanosoma cruzi Coaxes Cardiac Fibroblasts into Preventing Cardiomyocyte Death by Activating Nerve Growth Factor Receptor TrkA

Daniel Aridgides,
Ryan Salvador,
Mercio PereiraPerrin

Published: February 21, 2013
https://doi.org/10.1371/journal.pone.0057450

About the Authors

Daniel Aridgides

Affiliations Graduate Program in Immunology, Sackler School of Graduate Biomedical Sciences, Tufts University, Boston, Massachusetts, United States of America,, Department of Pathology, Tufts University School of Medicine, Boston, Massachusetts, United States of America

Ryan Salvador

Mercio PereiraPerrin

* E-mail: Mercio.perrin@tufts.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DA MP. Performed the experiments: DA RS. Analyzed the data: DA RS MP. Contributed reagents/materials/analysis tools: DA RS MP. Wrote the paper: DA MP.

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Fibroblasts
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Cardiomyocytes
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Trypanosoma cruzi
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Heart
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Enzyme-linked immunoassays
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Muscle cells
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Parasitic diseases
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Vimentin
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