About the Authors

Richard T. Davey Jr

rdavey@niaid.nih.gov

Affiliation National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

Ruth Lynfield

Affiliation Infectious Disease Division, Minnesota Department of Health, St. Paul, Minnesota, United States of America

Dominic E. Dwyer

Affiliation Department of Virology, Centre for Infectious Diseases and Microbiology, Westmead Hospital and University of Sydney, Westmead, New South Wales, Australia

Marcello H. Losso

Affiliation HIV Unit, Department of Medicine, Hospital José María Ramos Mejía, Buenos Aires, Argentina

Alessandro Cozzi-Lepri

Affiliation Research Department of Infection and Population Health, University College London, London, England, United Kingdom

Deborah Wentworth

Affiliation Division of Biostatistics, University of Minnesota, Minneapolis, Minnesota, United States of America

H. Clifford Lane

Affiliation National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

Robin Dewar

Affiliation Virus Isolation and Serology Laboratory, SAIC-Frederick, Inc., Frederick National Laboratory, Frederick, Maryland, United States of America

Adam Rupert

Affiliation AIDS Monitoring Laboratory, SAIC-Frederick, Inc., Frederick, Maryland, United States of America

Julia A. Metcalf

Affiliation National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

Sarah L. Pett

Affiliation Kirby Institute, Faculty of Medicine, University of New South Wales, Sydney, New South Wales, Australia

Timothy M. Uyeki

Affiliation Influenza Division, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

Jose Maria Bruguera

Affiliation Servicio de Inmunocomprometidos, Hospital José María Ramos Mejía, Buenos Aires, Argentina

Brian Angus

Affiliation Nuffield Department of Medicine, University of Oxford, Oxford, England, United Kingdom

Nathan Cummins

Affiliation Division of Infectious Diseases, Mayo Clinic, Rochester, Minnesota, United States of America

Jens Lundgren

Affiliation Department of Infectious Diseases, Copenhagen University Hospital/Rigshospitalet & University of Copenhagen, Copenhagen, Denmark

James D. Neaton

The Writing Group assumes responsibility for the manuscript. Membership of the INSIGHT FLU 002 & 003 Study Groups is included in the Acknowledgements.

Affiliation Division of Biostatistics, University of Minnesota, Minneapolis, Minnesota, United States of America

Competing Interests

Two of the co-authors, Robin Dewar and Adam Rupert, are employees of SAIC who perform bench laboratory research in support of NIAID studies but have no role in funding decisions made by their parent employer (SAIC). The authors declare that they have no other competing interests in regard to this manuscript. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials. One of the co-authors, Sarah Pett, is a PLOS ONE Editorial Board member. This does not alter the authors′ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Edited the manuscript: HCL SLP TMU JMB BA NC JL. Conceived and designed the experiments: RD. Performed the experiments: AR JAM. Analyzed the data: DW JDN AC-L. Wrote the paper: RTD RL DED MHL.