About the Authors

Franco Lombino

Affiliation Department of Microbiology & Immunology, Albert Einstein College of Medicine, Bronx, New York, United States of America

Fabrizio Biundo

Affiliation Department of Microbiology & Immunology, Albert Einstein College of Medicine, Bronx, New York, United States of America

Robert Tamayev

Affiliation Department of Microbiology & Immunology, Albert Einstein College of Medicine, Bronx, New York, United States of America

Ottavio Arancio

Affiliation Department of Pathology & Cell Biology, Taub Institute for Research on Alzheimer’s Disease and the Aging Brain, Columbia University, New York, New York, United States of America

Luciano D’Adamio

luciano.dadamio@einstein.yu.edu

Affiliation Department of Microbiology & Immunology, Albert Einstein College of Medicine, Bronx, New York, United States of America

Competing Interests

The AECOM has a patent on the commercial use of FDDKI mice. Luciano D’Adamio is a co-inventor on this patent. AECOM has licensed the patent to Remegenix, a company of which Luciano D’Adamio is a co-founder and a Board member. As a co-founder Luciano D’Adamio owns ∼35% of Remegenix. The patent and the licensing only covers commercial use of the mice and does not pose any obstacle to distribution of the mice to academic laboratories. There are no further patents, products in development or marketed products to declare. This does not alter the authors‚ adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: LD. Performed the experiments: LD FL FB RT. Analyzed the data: LD FL FB RT. Contributed reagents/materials/analysis tools: OA. Wrote the paper: LD.