About the Authors
- Sebastiano Collino
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* E-mail: sebastiano.collino@rd.nestle.com
Affiliation Proteomics and Metabonomics, Nestlé Institute of Health Sciences SA, Campus EPFL, Quartier de l'innovation, Lausanne, Switzerland
- Ivan Montoliu
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Affiliation Applied Mathematics, NESTEC SA, Nestlé Research Center, Lausanne, Switzerland
- François-Pierre J. Martin
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Affiliation Proteomics and Metabonomics, Nestlé Institute of Health Sciences SA, Campus EPFL, Quartier de l'innovation, Lausanne, Switzerland
- Max Scherer
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Affiliation Proteomics and Metabonomics, Nestlé Institute of Health Sciences SA, Campus EPFL, Quartier de l'innovation, Lausanne, Switzerland
- Daniela Mari
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Affiliations Department of Medical Sciences, University of Milan, Milan, Italy, Geriatric Unit Ca' Grande Foundation Maggiore Policlinico Hospital, Milan, Italy
- Stefano Salvioli
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Affiliations Department of Experimental Pathology, University of Bologna, Bologna, Italy, Interdepartmental Centre L. Galvani, University of Bologna, Bologna, Italy
- Laura Bucci
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Affiliations Department of Experimental Pathology, University of Bologna, Bologna, Italy, Interdepartmental Centre L. Galvani, University of Bologna, Bologna, Italy
- Rita Ostan
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Affiliations Department of Experimental Pathology, University of Bologna, Bologna, Italy, Interdepartmental Centre L. Galvani, University of Bologna, Bologna, Italy
- Daniela Monti
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Affiliation Department of Experimental Pathology and Oncology, University of Florence, Florence, Italy
- Elena Biagi
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Affiliation Department of Pharmaceutical Sciences, University of Bologna, Bologna, Italy
- Patrizia Brigidi
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Affiliation Department of Pharmaceutical Sciences, University of Bologna, Bologna, Italy
- Claudio Franceschi
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Affiliations Department of Experimental Pathology, University of Bologna, Bologna, Italy, Interdepartmental Centre L. Galvani, University of Bologna, Bologna, Italy
- Serge Rezzi
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Affiliation Proteomics and Metabonomics, Nestlé Institute of Health Sciences SA, Campus EPFL, Quartier de l'innovation, Lausanne, Switzerland
Competing Interests
Authors SC, FPM, MS, SR are employees of Nestlè Institute of Health Science SA. Author IM is an employee of Nestec S.A. There are no products in development or marketed products to declare. Five patents were filed based on the results presented in the paper. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.
Author Contributions
Performed the initial gut microbiota studies: EB PB. Provided samples from Down's Syndrome subjects: SS. Provided the aging cohort samples: D. Mari. Conceived and designed the experiments: CF. Performed the experiments: SC MS. Analyzed the data: FPM IM D. Monti LB RO. Contributed reagents/materials/analysis tools: MS. Wrote the paper: SC CF SR.