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Research Article

Targeting Src Family Kinases Inhibits Bevacizumab-Induced Glioma Cell Invasion

  • Deborah Huveldt,

    Affiliation: Department of Cancer Biology, Mayo Clinic, Jacksonville, Florida, United States of America

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  • Laura J. Lewis-Tuffin,

    Affiliation: Department of Cancer Biology, Mayo Clinic, Jacksonville, Florida, United States of America

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  • Brett L. Carlson,

    Affiliation: Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota, United States of America

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  • Mark A. Schroeder,

    Affiliation: Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota, United States of America

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  • Fausto Rodriguez,

    Affiliation: Department of Pathology, Mayo Clinic, Rochester, Minnesota, United States of America

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  • Caterina Giannini,

    Affiliation: Department of Pathology, Mayo Clinic, Rochester, Minnesota, United States of America

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  • Evanthia Galanis,

    Affiliation: Department of Oncology, Mayo Clinic, Rochester, Minnesota, United States of America

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  • Jann N. Sarkaria,

    Affiliation: Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota, United States of America

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  • Panos Z. Anastasiadis mail

    panos@mayo.edu

    Affiliation: Department of Cancer Biology, Mayo Clinic, Jacksonville, Florida, United States of America

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  • Published: February 14, 2013
  • DOI: 10.1371/journal.pone.0056505

About the Authors

Deborah Huveldt, Laura J. Lewis-Tuffin, Panos Z. Anastasiadis
Department of Cancer Biology, Mayo Clinic, Jacksonville, Florida, United States of America
Fausto Rodriguez, Caterina Giannini
Department of Pathology, Mayo Clinic, Rochester, Minnesota, United States of America
Evanthia Galanis
Department of Oncology, Mayo Clinic, Rochester, Minnesota, United States of America
Brett L. Carlson, Mark A. Schroeder, Jann N. Sarkaria
Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota, United States of America

Corresponding Author

Email: panos@mayo.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: EG JNS PZA. Performed the experiments: DH LJLT BLC MAS FR CG. Analyzed the data: DH LJLT CG JNS PZA. Wrote the paper: PZA.