About the Authors
- Annalisa Buniello
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Affiliations Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire, United Kingdom, Wolfson Centre for Age-Related Diseases, King's College London, London, United Kingdom
- Rachel E. Hardisty-Hughes
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Affiliation MRC Institute of Hearing Research, Nottingham, United Kingdom
- Johanna C. Pass
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Affiliations Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire, United Kingdom, Wolfson Centre for Age-Related Diseases, King's College London, London, United Kingdom
- Eva Bober
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Affiliation Max-Planck-Institute for Heart and Lung Research, Bad Nauheim, Germany
- Richard J. Smith
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Current address: University of Iowa, Iowa City, Iowa, United States of America
Affiliation MRC Institute of Hearing Research, Nottingham, United Kingdom
- Karen P. Steel
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* E-mail: karen.steel@kcl.ac.uk
Affiliations Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire, United Kingdom, Wolfson Centre for Age-Related Diseases, King's College London, London, United Kingdom, MRC Institute of Hearing Research, Nottingham, United Kingdom
Competing Interests
The authors have declared that no competing interests exist.
Author Contributions
Designed the experiments and carried out literature searches, in situ hybridisation, immunohistochemistry, quantitative RT-PCR, western blot, whole mount fluorescence, paintfilling, anatomical investigation and data analyses: AB. Analysed the behavior, made the 3D reconstruction of the inner ear and mapped the mutation: RHH. Provided the Hmx3KO mice and contributed to expression analyses: EB. Performed the genotyping and the neo counting: JCP. Carried out preliminary electrophysiological and anatomical investigation: RJS. Designed the research, obtained the funding, carried out electrophysiology and endocochlear potential measurements and interpreted the data: KPS. Approved the paper: AB RHH JCP EB RJS KPS. Conceived and designed the experiments: AB RHH KPS. Performed the experiments: AB RHH JCP EB RJS KPS. Analyzed the data: AB KPS. Contributed reagents/materials/analysis tools: KPS. Wrote the paper: AB KPS.