About the Authors

Tamer B. Shabaneh

Affiliations Norris Cotton Cancer Center, The Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire, United States of America, Department of Pharmacology and Toxicology, The Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire, United States of America

Sondra L. Downey

Affiliations Norris Cotton Cancer Center, The Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire, United States of America, Department of Pharmacology and Toxicology, The Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire, United States of America

Ayrton L. Goddard

Current address: Torbay Hospital, Newton Road, Torquay, Devon, United Kingdom

Affiliations Norris Cotton Cancer Center, The Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire, United States of America, Department of Pharmacology and Toxicology, The Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire, United States of America, Department of Biology & Biochemistry, University of Bath, Bath, United Kingdom

Michael Screen

Current address: Medical Research Council Toxicology Unit, University of Leicester, Lancaster Road, Leicester, United Kingdom

Affiliations Norris Cotton Cancer Center, The Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire, United States of America, Department of Pharmacology and Toxicology, The Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire, United States of America, Department of Biology & Biochemistry, University of Bath, Bath, United Kingdom

Marcella M. Lucas

Current address: Trinity Partners, Waltham, Massachusetts, United States of America

Affiliations Norris Cotton Cancer Center, The Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire, United States of America, Department of Pharmacology and Toxicology, The Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire, United States of America, Department of Biology & Biochemistry, University of Bath, Bath, United Kingdom

Alan Eastman

Affiliations Norris Cotton Cancer Center, The Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire, United States of America, Department of Pharmacology and Toxicology, The Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire, United States of America

Alexei F. Kisselev

Alexei.F.Kisselev@Dartmouth.edu

Affiliations Norris Cotton Cancer Center, The Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire, United States of America, Department of Pharmacology and Toxicology, The Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AFK AE TS. Performed the experiments: TBS SLD ALG MS MML AFK. Analyzed the data: AFK TBS SLD AE. Wrote the paper: AFK AE TS SLD.