Advertisement
Research Article

Mixed Modeling of Meta-Analysis P-Values (MixMAP) Suggests Multiple Novel Gene Loci for Low Density Lipoprotein Cholesterol

  • Andrea S. Foulkes mail,

    foulkes@schoolph.umass.edu

    Affiliation: Division of Biostatistics, School of Public Health and Health Sciences at the University of Massachusetts, Amherst, Massachusetts, United States of America

    X
  • Gregory J. Matthews,

    Affiliation: Division of Biostatistics, School of Public Health and Health Sciences at the University of Massachusetts, Amherst, Massachusetts, United States of America

    X
  • Ujjwal Das,

    Affiliation: Division of Biostatistics, School of Public Health and Health Sciences at the University of Massachusetts, Amherst, Massachusetts, United States of America

    X
  • Jane F. Ferguson,

    Affiliation: Cardiovascular Institute, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

    X
  • Rongheng Lin,

    Affiliation: Division of Biostatistics, School of Public Health and Health Sciences at the University of Massachusetts, Amherst, Massachusetts, United States of America

    X
  • Muredach P. Reilly

    Affiliation: Cardiovascular Institute, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

    X
  • Published: February 06, 2013
  • DOI: 10.1371/journal.pone.0054812

About the Authors

Andrea S. Foulkes, Gregory J. Matthews, Ujjwal Das, Rongheng Lin
Division of Biostatistics, School of Public Health and Health Sciences at the University of Massachusetts, Amherst, Massachusetts, United States of America
Jane F. Ferguson, Muredach P. Reilly
Cardiovascular Institute, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Corresponding Author

Email: foulkes@schoolph.umass.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: ASF GJM UD MPR. Performed the experiments: ASF GJM UD JFF. Analyzed the data: ASF GJM UD JFF. Contributed reagents/materials/analysis tools: ASF GJM UD RL. Wrote the paper: ASF MPR.