About the Authors

Dolores Hernán Pérez de la Ossa

Contributed equally to this work with: Dolores Hernán Pérez de la Ossa, Mar Lorente, Guillermo Velasco, Ana Isabel Torres-Suárez

Affiliation Department of Pharmacy and Pharmaceutical Technology, School of Pharmacy, Complutense University, Madrid, Spain

Mar Lorente

Contributed equally to this work with: Dolores Hernán Pérez de la Ossa, Mar Lorente, Guillermo Velasco, Ana Isabel Torres-Suárez

Affiliations Department of Biochemistry and Molecular Biology I, School of Biology, Complutense University, Madrid, Spain, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos, Madrid, Spain

Maria Esther Gil-Alegre

Affiliations Department of Pharmacy and Pharmaceutical Technology, School of Pharmacy, Complutense University, Madrid, Spain, Instituto de Farmacia Industrial, Complutense University, Madrid, Spain

Sofía Torres

Affiliation Department of Biochemistry and Molecular Biology I, School of Biology, Complutense University, Madrid, Spain

Elena García-Taboada

Affiliation Department of Biochemistry and Molecular Biology I, School of Biology, Complutense University, Madrid, Spain

María del Rosario Aberturas

Affiliation Department of Pharmacy and Pharmaceutical Technology, School of Pharmacy, Alcalá University, Madrid, Spain

Jesús Molpeceres

Affiliation Department of Pharmacy and Pharmaceutical Technology, School of Pharmacy, Alcalá University, Madrid, Spain

Guillermo Velasco

Contributed equally to this work with: Dolores Hernán Pérez de la Ossa, Mar Lorente, Guillermo Velasco, Ana Isabel Torres-Suárez

gvd@bbm1.ucm.es

Affiliations Department of Biochemistry and Molecular Biology I, School of Biology, Complutense University, Madrid, Spain, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos, Madrid, Spain

Ana Isabel Torres-Suárez

Contributed equally to this work with: Dolores Hernán Pérez de la Ossa, Mar Lorente, Guillermo Velasco, Ana Isabel Torres-Suárez

Affiliations Department of Pharmacy and Pharmaceutical Technology, School of Pharmacy, Complutense University, Madrid, Spain, Instituto de Farmacia Industrial, Complutense University, Madrid, Spain

Competing Interests

GW Pharmaceuticals funded part of the research that was performed in GV's laboratory. GV is a PLOS ONE Editorial Board member. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: GV AITS ML DH. Performed the experiments: DH ML MEG-A ST EG-T MRA JM. Analyzed the data: DH ML MEG-A GV. Contributed reagents/materials/analysis tools: MEG-A MRA JM AITS. Wrote the paper: GV DH ML.