Advertisement
Research Article

Accelerated Cell Aging in Female APOE-ε4 Carriers: Implications for Hormone Therapy Use

  • Emily G. Jacobs mail,

    egjacobs@nmr.mgh.harvard.edu (EGJ); nrasgon@stanford.edu (NLR)

    Affiliation: Robert Wood Johnson Foundation Health and Society Scholars Program, Center for Health and Community, University of California San Francisco, San Francisco, California, United States of America

    Current address: Departments of Psychiatry and Medicine, Harvard Medical School, Boston, Massachusetts, United States of America

    X
  • Candyce Kroenke,

    Affiliation: Kaiser Permanente Division of Research, Oakland, California, United States of America

    X
  • Jue Lin,

    Affiliation: Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, California, United States of America

    X
  • Elissa S. Epel,

    Affiliation: Department of Psychiatry, University of California San Francisco, San Francisco, California, United States of America

    X
  • Heather A. Kenna,

    Affiliation: Stanford Center for Neuroscience in Women's Health, Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California, United States of America

    X
  • Elizabeth H. Blackburn,

    Affiliation: Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, California, United States of America

    X
  • Natalie L. Rasgon mail

    egjacobs@nmr.mgh.harvard.edu (EGJ); nrasgon@stanford.edu (NLR)

    Affiliation: Stanford Center for Neuroscience in Women's Health, Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California, United States of America

    X
  • Published: February 13, 2013
  • DOI: 10.1371/journal.pone.0054713

About the Authors

Emily G. Jacobs
Robert Wood Johnson Foundation Health and Society Scholars Program, Center for Health and Community, University of California San Francisco, San Francisco, California, United States of America
Candyce Kroenke
Kaiser Permanente Division of Research, Oakland, California, United States of America
Jue Lin, Elizabeth H. Blackburn
Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, California, United States of America
Elissa S. Epel
Department of Psychiatry, University of California San Francisco, San Francisco, California, United States of America
Heather A. Kenna, Natalie L. Rasgon
Stanford Center for Neuroscience in Women's Health, Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California, United States of America

Corresponding Authors

Competing Interests

The authors have read the journal's policy and have the following conflicts: Drs. Blackburn, Epel, and Lin are cofounders in a company measuring telomere diagnostics. No other author has a conflict of interest to report. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: EJ NR EE. Performed the experiments: EE NR JL. Analyzed the data: EJ CK. Contributed reagents/materials/analysis tools: JL EB NR EE. Wrote the paper: EJ NR JL EE. Administrative and technical support: HK.