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Research Article

Population Biology of Streptococcus pneumoniae in West Africa: Multilocus Sequence Typing of Serotypes That Exhibit Different Predisposition to Invasive Disease and Carriage

  • Eric S. Donkor,

    Affiliations: Department of Pathogen Molecular Biology, London School of Hygiene and Tropical Medicine, London, United Kingdom, Department of Microbiology, University of Ghana Medical School, Accra, Ghana

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  • Richard A. Adegbola,

    Affiliation: GlaxoSmithKline Vaccines, Wavre, Belgium

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  • Brendan W. Wren,

    Affiliation: Department of Pathogen Molecular Biology, London School of Hygiene and Tropical Medicine, London, United Kingdom

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  • Martin Antonio mail

    mantonio@mrc.gm

    Affiliation: Vaccinology Theme, Medical Research Council, Fajara, The Gambia

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  • Published: January 16, 2013
  • DOI: 10.1371/journal.pone.0053925

About the Authors

Eric S. Donkor, Brendan W. Wren
Department of Pathogen Molecular Biology, London School of Hygiene and Tropical Medicine, London, United Kingdom
Martin Antonio
Vaccinology Theme, Medical Research Council, Fajara, The Gambia
Richard A. Adegbola
GlaxoSmithKline Vaccines, Wavre, Belgium
Eric S. Donkor
Department of Microbiology, University of Ghana Medical School, Accra, Ghana

Corresponding Author

Email: mantonio@mrc.gm

Competing Interests

Richard A. Adegbola is an employee of GlaxoSmithKline Vaccines in Belgium and received previous grant awards for pneumococcal carriage studies whilst working as an employee of the UK MRC Unit in The Gambia. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials. The other authors have no conflict of interest to declare.

Author Contributions

Gave approval for publication of the manuscript: ESD MA RAA BWW. Conceived and designed the experiments: MA RAA BWW. Performed the experiments: ESD. Analyzed the data: ESD. Contributed reagents/materials/analysis tools: MA RAA BWW. Wrote the paper: ESD MA RAA BWW.