About the Authors

Loren Baugh

Affiliations Seattle Structural Genomics Center for Infectious Disease, Seattle, Washington, United States of America, Seattle Biomedical Research Institute, Seattle, Washington, United States of America

Larry A. Gallagher

Affiliation Department of Genome Sciences, University of Washington, Seattle, Washington, United States of America

Rapatbhorn Patrapuvich

Affiliation Department of Genome Sciences, University of Washington, Seattle, Washington, United States of America

Matthew C. Clifton

Affiliations Seattle Structural Genomics Center for Infectious Disease, Seattle, Washington, United States of America, Emerald BioStructures, Bainbridge Island, Washington, United States of America

Anna S. Gardberg

Affiliation Emerald BioStructures, Bainbridge Island, Washington, United States of America

Thomas E. Edwards

Affiliations Seattle Structural Genomics Center for Infectious Disease, Seattle, Washington, United States of America, Emerald BioStructures, Bainbridge Island, Washington, United States of America

Brianna Armour

Affiliation Emerald BioStructures, Bainbridge Island, Washington, United States of America

Darren W. Begley

Affiliations Seattle Structural Genomics Center for Infectious Disease, Seattle, Washington, United States of America, Emerald BioStructures, Bainbridge Island, Washington, United States of America

Shellie H. Dieterich

Affiliation Emerald BioStructures, Bainbridge Island, Washington, United States of America

David M. Dranow

Affiliation Emerald BioStructures, Bainbridge Island, Washington, United States of America

Jan Abendroth

Affiliations Seattle Structural Genomics Center for Infectious Disease, Seattle, Washington, United States of America, Emerald BioStructures, Bainbridge Island, Washington, United States of America

James W. Fairman

Affiliation Emerald BioStructures, Bainbridge Island, Washington, United States of America

David Fox III

Affiliation Emerald BioStructures, Bainbridge Island, Washington, United States of America

Bart L. Staker

Affiliations Seattle Structural Genomics Center for Infectious Disease, Seattle, Washington, United States of America, Emerald BioStructures, Bainbridge Island, Washington, United States of America

Isabelle Phan

Affiliations Seattle Structural Genomics Center for Infectious Disease, Seattle, Washington, United States of America, Seattle Biomedical Research Institute, Seattle, Washington, United States of America

Angela Gillespie

Affiliations Seattle Structural Genomics Center for Infectious Disease, Seattle, Washington, United States of America, Department of Medicine, Division of Allergy and Infectious Disease, University of Washington, Seattle, Washington, United States of America

Ryan Choi

Affiliations Seattle Structural Genomics Center for Infectious Disease, Seattle, Washington, United States of America, Department of Medicine, Division of Allergy and Infectious Disease, University of Washington, Seattle, Washington, United States of America

Steve Nakazawa-Hewitt

Affiliations Seattle Structural Genomics Center for Infectious Disease, Seattle, Washington, United States of America, Department of Medicine, Division of Allergy and Infectious Disease, University of Washington, Seattle, Washington, United States of America

Mary Trang Nguyen

Affiliations Seattle Structural Genomics Center for Infectious Disease, Seattle, Washington, United States of America, Department of Medicine, Division of Allergy and Infectious Disease, University of Washington, Seattle, Washington, United States of America

Alberto Napuli

Affiliations Seattle Structural Genomics Center for Infectious Disease, Seattle, Washington, United States of America, Department of Medicine, Division of Allergy and Infectious Disease, University of Washington, Seattle, Washington, United States of America

Lynn Barrett

Affiliations Seattle Structural Genomics Center for Infectious Disease, Seattle, Washington, United States of America, Department of Medicine, Division of Allergy and Infectious Disease, University of Washington, Seattle, Washington, United States of America

Garry W. Buchko

Affiliations Seattle Structural Genomics Center for Infectious Disease, Seattle, Washington, United States of America, Biological Sciences Division, Pacific Northwest National Laboratory, Richland, Washington, United States of America

Robin Stacy

Affiliations Seattle Structural Genomics Center for Infectious Disease, Seattle, Washington, United States of America, Seattle Biomedical Research Institute, Seattle, Washington, United States of America

Peter J. Myler

Affiliations Seattle Structural Genomics Center for Infectious Disease, Seattle, Washington, United States of America, Seattle Biomedical Research Institute, Seattle, Washington, United States of America, Department of Global Health, University of Washington, Seattle, Washington, United States of America, Department of Medical Education and Biomedical Informatics, University of Washington, Seattle, Washington

Lance J. Stewart

Affiliations Seattle Structural Genomics Center for Infectious Disease, Seattle, Washington, United States of America, Emerald BioStructures, Bainbridge Island, Washington, United States of America

Colin Manoil

Affiliation Department of Genome Sciences, University of Washington, Seattle, Washington, United States of America

Wesley C. Van Voorhis

wesley@uw.edu

Affiliations Seattle Structural Genomics Center for Infectious Disease, Seattle, Washington, United States of America, Department of Medicine, Division of Allergy and Infectious Disease, University of Washington, Seattle, Washington, United States of America, Department of Global Health, University of Washington, Seattle, Washington, United States of America, Department of Microbiology, University of Washington, Seattle, Washington, United States of America

Competing Interests

The authors declare affiliation of several authors with a commercial company, Emerald BioStructures, as indicated in the author affiliation list. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: WCVV LAG RP BLS IP L. Barrett GWB RS PJM LJS CM. Performed the experiments: LAG RP MCC ASG TEE BA DWB SHD DMD JA JWF DFIII BLS IP AG RC SNH MTN AN. Analyzed the data: L. Baugh WCVV LAG RP MCC ASG TEE BA DWB SHD DMD JA JWF DFIII BLS IP L. Barrett AG RC SNH MTN AN GWB RS PJM LJS CM. Contributed reagents/materials/analysis tools: LAG RP MCC ASG TEE BA DWB SHD DMD JA JWF DFIII BLS IP L. Barrett AG RC SNH MTN AN. Wrote the paper: L. Baugh WCVV LAG RP MCC ASG TEE BA DWB SHD DMD JA JWF DFIII BLS IP L. Barrett AG RC SNH MTN AN GWB RS PJM LJS CM.