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Research Article

Germline DNA Copy Number Aberrations Identified as Potential Prognostic Factors for Breast Cancer Recurrence

  • Yadav Sapkota,

    Affiliations: Cross Cancer Institute, Alberta Health Services, Edmonton, Alberta, Canada, Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, Alberta, Canada

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  • Sunita Ghosh,

    Affiliations: Cross Cancer Institute, Alberta Health Services, Edmonton, Alberta, Canada, Department of Oncology, University of Alberta, Edmonton, Alberta, Canada

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  • Raymond Lai,

    Affiliations: Cross Cancer Institute, Alberta Health Services, Edmonton, Alberta, Canada, Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, Alberta, Canada

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  • Bradley P. Coe,

    Affiliation: Department of Genome Sciences, University of Washington, School of Medicine, Seattle, Washington, United States of America

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  • Carol E. Cass,

    Affiliations: Cross Cancer Institute, Alberta Health Services, Edmonton, Alberta, Canada, Department of Oncology, University of Alberta, Edmonton, Alberta, Canada

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  • Yutaka Yasui,

    Affiliation: Department of Public Health Sciences, University of Alberta, Edmonton, Alberta, Canada

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  • John R. Mackey,

    Affiliations: Cross Cancer Institute, Alberta Health Services, Edmonton, Alberta, Canada, Department of Oncology, University of Alberta, Edmonton, Alberta, Canada

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  • Sambasivarao Damaraju mail

    Sambasivarao.Damaraju@albertahealthservices.ca

    Affiliations: Cross Cancer Institute, Alberta Health Services, Edmonton, Alberta, Canada, Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, Alberta, Canada

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  • Published: January 16, 2013
  • DOI: 10.1371/journal.pone.0053850

About the Authors

Yadav Sapkota, Sunita Ghosh, Raymond Lai, Carol E. Cass, John R. Mackey, Sambasivarao Damaraju
Cross Cancer Institute, Alberta Health Services, Edmonton, Alberta, Canada
Yadav Sapkota, Raymond Lai, Sambasivarao Damaraju
Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, Alberta, Canada
Sunita Ghosh, Carol E. Cass, John R. Mackey
Department of Oncology, University of Alberta, Edmonton, Alberta, Canada
Bradley P. Coe
Department of Genome Sciences, University of Washington, School of Medicine, Seattle, Washington, United States of America
Yutaka Yasui
Department of Public Health Sciences, University of Alberta, Edmonton, Alberta, Canada

Corresponding Author

Email: Sambasivarao.Damaraju@albertahealthservices.ca

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Offered critical reading of manuscript and constructive suggestions: CEC JRM YY RL. Offered medical oncology perspectives: JRM. Conceived and directed the project: SD. Conceived and designed the experiments: SD. Performed the experiments: YS. Analyzed the data: YS SG. Contributed reagents/materials/analysis tools: BPC YS SG YY. Wrote the paper: SD YS.