About the Authors

Urmi Bandyopadhyay

Contributed equally to this work with: Urmi Bandyopadhyay, Justin Cotney

Affiliations Department of Genetics, Yale University School of Medicine, New Haven, Connecticut, United States of America, Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, Connecticut, United States of America

Justin Cotney

Contributed equally to this work with: Urmi Bandyopadhyay, Justin Cotney

Affiliation Department of Genetics, Yale University School of Medicine, New Haven, Connecticut, United States of America

Maria Nagy

Affiliations Department of Genetics, Yale University School of Medicine, New Haven, Connecticut, United States of America, Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, Connecticut, United States of America

Sunghee Oh

Current address: Division of Human Genetics, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America

Affiliation Department of Genetics, Yale University School of Medicine, New Haven, Connecticut, United States of America

Jing Leng

Affiliations Department of Genetics, Yale University School of Medicine, New Haven, Connecticut, United States of America, Program in Computational Biology and Bioinformatics, Yale University, New Haven, Connecticut, United States of America

Milind Mahajan

Current address: Genomics Core Facility, Department of Genetics and Genomic Sciences, Mount Sinai School of Medicine, New York, New York, United States of America

Affiliation Department of Genetics, Yale University School of Medicine, New Haven, Connecticut, United States of America

Shrikant Mane

Affiliation Department of Genetics, Yale University School of Medicine, New Haven, Connecticut, United States of America

Wayne A. Fenton

Affiliation Department of Genetics, Yale University School of Medicine, New Haven, Connecticut, United States of America

James P. Noonan

Affiliations Department of Genetics, Yale University School of Medicine, New Haven, Connecticut, United States of America, Kavli Institute for Neuroscience, Yale University School of Medicine, New Haven, Connecticut, United States of America, Program in Computational Biology and Bioinformatics, Yale University, New Haven, Connecticut, United States of America

Arthur L. Horwich

arthur.horwich@yale.edu

Affiliations Department of Genetics, Yale University School of Medicine, New Haven, Connecticut, United States of America, Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, Connecticut, United States of America, Kavli Institute for Neuroscience, Yale University School of Medicine, New Haven, Connecticut, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: UB JC WAF JPN ALH. Performed the experiments: UB JC MN MM SM. Analyzed the data: UB JC SO JL WAF JPN. Wrote the paper: UB JC WAF JPN ALH.