About the Authors

Martin Neumann

Affiliation Charité, University Hospital Berlin, Campus Benjamin Franklin, Department of Hematology and Oncology, Berlin, Germany

Ebru Coskun

Affiliation Charité, University Hospital Berlin, Campus Benjamin Franklin, Department of Hematology and Oncology, Berlin, Germany

Lars Fransecky

Affiliation Charité, University Hospital Berlin, Campus Benjamin Franklin, Department of Hematology and Oncology, Berlin, Germany

Liliana H. Mochmann

Affiliation Charité, University Hospital Berlin, Campus Benjamin Franklin, Department of Hematology and Oncology, Berlin, Germany

Isabelle Bartram

Affiliation Charité, University Hospital Berlin, Campus Benjamin Franklin, Department of Hematology and Oncology, Berlin, Germany

Nasrin Farhadi Sartangi

Affiliation Charité, University Hospital Berlin, Campus Benjamin Franklin, Department of Hematology and Oncology, Berlin, Germany

Sandra Heesch

Affiliation Charité, University Hospital Berlin, Campus Benjamin Franklin, Department of Hematology and Oncology, Berlin, Germany

Nicola Gökbuget

Affiliation Goethe University Hospital, Department of Medicine II, Hematology and Oncology, Frankfurt/Main, Germany

Stefan Schwartz

Affiliation Charité, University Hospital Berlin, Campus Benjamin Franklin, Department of Hematology and Oncology, Berlin, Germany

Christian Brandts

Affiliation Goethe University Hospital, Department of Medicine II, Hematology and Oncology, Frankfurt/Main, Germany

Cornelia Schlee

Affiliation Charité, University Hospital Berlin, Campus Benjamin Franklin, Department of Hematology and Oncology, Berlin, Germany

Rainer Haas

Affiliation Department of Hematology and Oncology, University of Düsseldorf, Düsseldorf, Germany

Ulrich Dührsen

Affiliation Department of Hematology and Oncology, University of Essen, Essen, Germany

Martin Griesshammer

Affiliation Department of Hematology and Oncology, Klinikum Minden, Minden, Germany

Hartmut Döhner

Affiliation Department of Internal Medicine III, University of Ulm, Ulm, Germany

Gerhard Ehninger

Affiliation Department of Hematology and Oncology, University of Dresden, Dresden, Germany

Thomas Burmeister

Affiliation Charité, University Hospital Berlin, Campus Benjamin Franklin, Department of Hematology and Oncology, Berlin, Germany

Olga Blau

Affiliation Charité, University Hospital Berlin, Campus Benjamin Franklin, Department of Hematology and Oncology, Berlin, Germany

Eckhard Thiel

Affiliation Charité, University Hospital Berlin, Campus Benjamin Franklin, Department of Hematology and Oncology, Berlin, Germany

Dieter Hoelzer

Affiliation Goethe University Hospital, Department of Medicine II, Hematology and Oncology, Frankfurt/Main, Germany

Wolf-Karsten Hofmann

Affiliation University Hospital Mannheim, Department of Hematology and Oncology, Mannheim, Germany

Claudia D. Baldus

claudia.baldus@charite.de

Affiliation Charité, University Hospital Berlin, Campus Benjamin Franklin, Department of Hematology and Oncology, Berlin, Germany

Competing Interests

TKI258 was a kind gift from Novartis (Basel, Switzerland). There are no further patents, products in development or marketed products to declare. This does not alter the authors‚ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: MN NG DH ET CDB. Performed the experiments: MN EC LF LM IB NFS SH SS CS OB. Analyzed the data: MN EC TB CDB. Contributed reagents/materials/analysis tools: CB RH UD MG HD GE. Wrote the paper: MN EC SS WKH CDB.