About the Authors

Sheng-Han Kuo

Affiliation Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, New York, United States of America

Guomei Tang

Affiliation Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, New York, United States of America

Karen Ma

Affiliation GH Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, New York, United States of America

Rachel Babij

Affiliation GH Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, New York, United States of America

Etty Cortes

Affiliations Taub Institute for Research on Alzheimer's Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, New York, United States of America, Department of Pathology and Cell Biology, Columbia University Medical Center and the New York Presbyterian Hospital, New York, New York, United States of America

Jean-Paul G. Vonsattel

Affiliations Taub Institute for Research on Alzheimer's Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, New York, United States of America, Department of Pathology and Cell Biology, Columbia University Medical Center and the New York Presbyterian Hospital, New York, New York, United States of America

Phyllis L. Faust

Affiliation Department of Pathology and Cell Biology, Columbia University Medical Center and the New York Presbyterian Hospital, New York, New York, United States of America

David Sulzer

Affiliation Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, New York, United States of America

Elan D. Louis

EDL2@columbia.edu

Affiliations Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, New York, United States of America, GH Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, New York, United States of America, Taub Institute for Research on Alzheimer's Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, New York, United States of America, Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SHK GT PF DS EL. Performed the experiments: SHK GT. Analyzed the data: SHK EL. Contributed reagents/materials/analysis tools: KM RB EC JV. Wrote the paper: SHK GT PF DS EL.