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Research Article

RET/GFRα Signals Are Dispensable for Thymic T Cell Development In Vivo

  • Afonso Rocha Martins Almeida,

    Affiliation: Instituto de Medicina Molecular, Faculdade de Medicina de Lisboa, Lisboa, Portugal

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  • Sílvia Arroz-Madeira,

    Affiliation: Instituto de Medicina Molecular, Faculdade de Medicina de Lisboa, Lisboa, Portugal

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  • Diogo Fonseca-Pereira,

    Affiliation: Instituto de Medicina Molecular, Faculdade de Medicina de Lisboa, Lisboa, Portugal

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  • Hélder Ribeiro,

    Affiliation: Instituto de Medicina Molecular, Faculdade de Medicina de Lisboa, Lisboa, Portugal

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  • Reena Lasrado,

    Affiliation: Division of Molecular Neurobiology, Medical Research Council (MRC), National Institute for Medical Research, London, United Kingdom

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  • Vassilis Pachnis,

    Affiliation: Division of Molecular Neurobiology, Medical Research Council (MRC), National Institute for Medical Research, London, United Kingdom

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  • Henrique Veiga-Fernandes mail

    jhfernandes@fm.ul.pt

    Affiliation: Instituto de Medicina Molecular, Faculdade de Medicina de Lisboa, Lisboa, Portugal

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  • Published: December 27, 2012
  • DOI: 10.1371/journal.pone.0052949

About the Authors

Afonso Rocha Martins Almeida, Sílvia Arroz-Madeira, Diogo Fonseca-Pereira, Hélder Ribeiro, Henrique Veiga-Fernandes
Instituto de Medicina Molecular, Faculdade de Medicina de Lisboa, Lisboa, Portugal
Reena Lasrado, Vassilis Pachnis
Division of Molecular Neurobiology, Medical Research Council (MRC), National Institute for Medical Research, London, United Kingdom

Corresponding Author

Email: jhfernandes@fm.ul.pt

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: ARMA HV-F. Performed the experiments: ARMA SA-M DF-P HR HV-F. Analyzed the data: ARMA SA-M DF-P HR HV-F. Contributed reagents/materials/analysis tools: RL VP. Wrote the paper: ARMA HV-F.