About the Authors

Line D. Rasmussen

linedahlerup@hotmail.com (LDR); niels.obel@rh.regionh.dk (NO)

Affiliation Department of Infectious Diseases, Odense University Hospital, Odense, Denmark

Gitte Kronborg

Affiliation Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Denmark

Carsten S. Larsen

Affiliation Department of Infectious Diseases, Aarhus University Hospital, Skejby, Denmark

Court Pedersen

Affiliation Department of Infectious Diseases, Odense University Hospital, Odense, Denmark

Jan Gerstoft

Affiliation Department of Infectious Diseases, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark

Niels Obel

linedahlerup@hotmail.com (LDR); niels.obel@rh.regionh.dk (NO)

Affiliation Department of Infectious Diseases, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark

Competing Interests

NO has received research funding from Roche, Bristol-Myers Squibb, Merck Sharp & Dohme, GlaxoSmithKline, Abbott, Boehringer Ingelheim, Janssen-Cilag and Swedish Orphan Drugs. CP has received research funding from Abbott, Gilead and Merck Sharp & Dohme. JG has received research funding from Abbott, Roche, Bristol-Myers Squibb, Merck Sharp & Dohme, Pharmasia, GlaxoSmithKline, Swedish Orphan Drugs and Boehringer Ingelheim. CSL has received research funding from Baxter and Crucell/SBL vaccines. GK and LDR report no conflicts of interest. The potential conflicts of interest described above do not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conducted the literature review: LDR. Statistical expertise: LDR NO. Revised the article critically for important intellectual content: LDR GK CSL CP JG NO. Performed the final approval of the article: LDR GK CSL CP JG NO. Obtained the funding: CP GK CSL JG NO. Performed the administrative, technical, or logistic support: LDR NO. Conceived and designed the experiments: LDR JG NO. Analyzed the data: LDR GK CSL CP JG NO. Contributed reagents/materials/analysis tools: CP GK CSL JG NO. Wrote the paper: LDR.