About the Authors

Xianfeng Zhang

Affiliation Institute for Genetic Medicine, Hokkaido University, Kita-ku, Sapporo, Japan

Tomoyoshi Sobue

Affiliation Institute for Genetic Medicine, Hokkaido University, Kita-ku, Sapporo, Japan

Mao Isshiki

Affiliation Institute for Genetic Medicine, Hokkaido University, Kita-ku, Sapporo, Japan

Shun-ichi Makino

Affiliation Institute for Genetic Medicine, Hokkaido University, Kita-ku, Sapporo, Japan

Makoto Inoue

Affiliation DNAVEC Corporation, Techno Park Oho, Tsukuba, Ibaraki, Japan

Kazunori Kato

Affiliation Department of BioMedical Engineering, Toyo University, Kawagoe, Saitama, Japan

Tatsuo Shioda

Affiliation Department of Viral Infection, Research Institute for Microbial Disease, Osaka University, Yamada-oka, Suita-shi, Osaka, Japan

Takashi Ohashi

Affiliation Institute for Genetic Medicine, Hokkaido University, Kita-ku, Sapporo, Japan

Hirotaka Sato

Affiliation Institute for Genetic Medicine, Hokkaido University, Kita-ku, Sapporo, Japan

Jun Komano

Affiliation Division of Virology, Department of Infectious Diseases, Osaka Prefectural Institute of Public Health, Nakamichi Higashinari-ku, Osaka, Japan

Hideji Hanabusa

Affiliation Ogikubo Hospital, Ogikubo, Suginami, Tokyo, Japan

Hisatoshi Shida

hshida@igm.hokudai.ac.jp

Affiliation Institute for Genetic Medicine, Hokkaido University, Kita-ku, Sapporo, Japan

Competing Interests

The authors declare one author, M. Inoue, has an affiliation in DNAVEC Corporation. Although DNAVEC, a profit company, has developed and is preparing for marketing the Sendai Virus Vector (SeV Vector), it has not financially supported this study at all. This study has been exclusively supported by the grants (No: 21390135) of Ministry of Education, Culture, Sports, Science and Technology and that (No: SAB4861) of Human Health Foundation. Thus, participation of Makoto Inoue, a member of DNAVEC, does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: XZ H. Shida. Performed the experiments: XZ T. Sobue M. Isshiki SM H. Sato. Analyzed the data: XZ T. Sobue M. Isshiki SM H. Shida. Contributed reagents/materials/analysis tools: M. Inoue KK T. Shioda TO JK HH. Wrote the paper: XZ H. Shida.