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Research Article

Elevation in Inflammatory Serum Biomarkers Predicts Response to Trastuzumab-Containing Therapy

  • Ahmed A. Alkhateeb,

    Affiliation: Department of Neurosurgery, The Pennsylvania State University Hershey Medical Center, Hershey, Pennsylvania, United States of America

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  • Kim Leitzel,

    Affiliation: Division of Hematology-Medical Oncology, The Pennsylvania State University Hershey Medical Center, Hershey, Pennsylvania, United States of America

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  • Suhail M. Ali,

    Affiliations: Division of Hematology-Medical Oncology, The Pennsylvania State University Hershey Medical Center, Hershey, Pennsylvania, United States of America, Department of Medicine, Lebanon VA Medical Center, Lebanon, Pennsylvania, United States of America

    X
  • Cynthia Campbell-Baird,

    Affiliation: Division of Hematology-Medical Oncology, The Pennsylvania State University Hershey Medical Center, Hershey, Pennsylvania, United States of America

    X
  • Matthew Evans,

    Affiliation: Division of Hematology-Medical Oncology, The Pennsylvania State University Hershey Medical Center, Hershey, Pennsylvania, United States of America

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  • Eva-Maria Fuchs,

    Affiliation: Department of Medicine, Medical University of Vienna, Vienna, Austria

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  • Wolfgang J. Köstler,

    Affiliation: Department of Medicine, Medical University of Vienna, Vienna, Austria

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  • Allan Lipton,

    Affiliation: Division of Hematology-Medical Oncology, The Pennsylvania State University Hershey Medical Center, Hershey, Pennsylvania, United States of America

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  • James Connor mail

    jconnor@hmc.psu.edu

    Affiliation: Department of Neurosurgery, The Pennsylvania State University Hershey Medical Center, Hershey, Pennsylvania, United States of America

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  • Published: December 26, 2012
  • DOI: 10.1371/journal.pone.0051379

About the Authors

Ahmed A. Alkhateeb, James Connor
Department of Neurosurgery, The Pennsylvania State University Hershey Medical Center, Hershey, Pennsylvania, United States of America
Kim Leitzel, Suhail M. Ali, Cynthia Campbell-Baird, Matthew Evans, Allan Lipton
Division of Hematology-Medical Oncology, The Pennsylvania State University Hershey Medical Center, Hershey, Pennsylvania, United States of America
Suhail M. Ali
Department of Medicine, Lebanon VA Medical Center, Lebanon, Pennsylvania, United States of America
Eva-Maria Fuchs, Wolfgang J. Köstler
Department of Medicine, Medical University of Vienna, Vienna, Austria

Corresponding Author

Email: jconnor@hmc.psu.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JC AA AL WK. Performed the experiments: AA SA. Analyzed the data: AA SA KL. Contributed reagents/materials/analysis tools: SA KL CC ME EF WK. Wrote the paper: AA. Collection of sample: CC ME EF WK KL AL.