Advertisement
Research Article

Acute Manipulation of Diacylglycerol Reveals Roles in Nuclear Envelope Assembly & Endoplasmic Reticulum Morphology

  • Marie-Charlotte Domart equal contributor,

    equal contributor Contributed equally to this work with: Marie-Charlotte Domart, Tina M. C. Hobday

    Affiliation: Cell Biophysics Laboratory, London Research Institute, Cancer Research United Kingdom, London, United Kingdom

    X
  • Tina M. C. Hobday equal contributor,

    equal contributor Contributed equally to this work with: Marie-Charlotte Domart, Tina M. C. Hobday

    Affiliation: Cell Biophysics Laboratory, London Research Institute, Cancer Research United Kingdom, London, United Kingdom

    X
  • Christopher J. Peddie,

    Affiliation: Electron Microscopy Unit, London Research Institute, Cancer Research United Kingdom, London, United Kingdom

    X
  • Gary H. C. Chung,

    Affiliation: Cell Biophysics Laboratory, London Research Institute, Cancer Research United Kingdom, London, United Kingdom

    X
  • Alan Wang,

    Affiliation: Department of Biology, Amherst College, Amherst, Massachusetts, United States of America

    X
  • Karen Yeh,

    Affiliation: Department of Biology, Amherst College, Amherst, Massachusetts, United States of America

    X
  • Nirmal Jethwa,

    Affiliation: Cell Biophysics Laboratory, London Research Institute, Cancer Research United Kingdom, London, United Kingdom

    X
  • Qifeng Zhang,

    Affiliation: The Babraham Institute, Babraham Research Campus, Cambridge, United Kingdom

    X
  • Michael J. O. Wakelam,

    Affiliation: The Babraham Institute, Babraham Research Campus, Cambridge, United Kingdom

    X
  • Rudiger Woscholski,

    Affiliation: Department of Chemistry, Faculty of Natural Sciences and Institute of Chemical Biology, Imperial College London, London, United Kingdom

    X
  • Richard D. Byrne,

    Affiliation: Cell Biophysics Laboratory, London Research Institute, Cancer Research United Kingdom, London, United Kingdom

    X
  • Lucy M. Collinson,

    Affiliation: Electron Microscopy Unit, London Research Institute, Cancer Research United Kingdom, London, United Kingdom

    X
  • Dominic L. Poccia,

    Affiliation: Department of Biology, Amherst College, Amherst, Massachusetts, United States of America

    X
  • Banafshé Larijani mail

    banafshe.larijani@cancer.org.uk

    Affiliation: Cell Biophysics Laboratory, London Research Institute, Cancer Research United Kingdom, London, United Kingdom

    X
  • Published: December 05, 2012
  • DOI: 10.1371/journal.pone.0051150

About the Authors

Marie-Charlotte Domart, Tina M. C. Hobday, Gary H. C. Chung, Nirmal Jethwa, Richard D. Byrne, Banafshé Larijani
Cell Biophysics Laboratory, London Research Institute, Cancer Research United Kingdom, London, United Kingdom
Christopher J. Peddie, Lucy M. Collinson
Electron Microscopy Unit, London Research Institute, Cancer Research United Kingdom, London, United Kingdom
Alan Wang, Karen Yeh, Dominic L. Poccia
Department of Biology, Amherst College, Amherst, Massachusetts, United States of America
Qifeng Zhang, Michael J. O. Wakelam
The Babraham Institute, Babraham Research Campus, Cambridge, United Kingdom
Rudiger Woscholski
Department of Chemistry, Faculty of Natural Sciences and Institute of Chemical Biology, Imperial College London, London, United Kingdom

Corresponding Author

Email: banafshe.larijani@cancer.org.uk

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: BL DLP MCD LMC. Performed the experiments: MCD TMCH CJP GHCC AW KY NJ QZ. Analyzed the data: BL DLP MCD QZ RDB LMC MJOW. Contributed reagents/materials/analysis tools: RW MJOW. Wrote the paper: BL DLP.