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Research Article

The Complex Exogenous RNA Spectra in Human Plasma: An Interface with Human Gut Biota?

  • Kai Wang mail,

    kwang@systemsbiology.org (KW); dgalas@pnri.org (DG); paul.wilmes@uni.lu (PW)

    Affiliation: Institute for Systems Biology, Seattle, Washington, United States of America

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  • Hong Li,

    Affiliation: Institute for Systems Biology, Seattle, Washington, United States of America

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  • Yue Yuan,

    Affiliation: Institute for Systems Biology, Seattle, Washington, United States of America

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  • Alton Etheridge,

    Affiliations: Institute for Systems Biology, Seattle, Washington, United States of America, Pacific Northwest Diabetes Research, Seattle, Washington, United States of America

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  • Yong Zhou,

    Affiliation: Institute for Systems Biology, Seattle, Washington, United States of America

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  • David Huang,

    Affiliations: Institute for Systems Biology, Seattle, Washington, United States of America, Pacific Northwest Diabetes Research, Seattle, Washington, United States of America

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  • Paul Wilmes mail,

    kwang@systemsbiology.org (KW); dgalas@pnri.org (DG); paul.wilmes@uni.lu (PW)

    Affiliation: Luxembourg Center for Systems Biomedicine, University of Luxembourg, Luxembourg City, Luxembourg

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  • David Galas mail

    kwang@systemsbiology.org (KW); dgalas@pnri.org (DG); paul.wilmes@uni.lu (PW)

    Affiliations: Institute for Systems Biology, Seattle, Washington, United States of America, Luxembourg Center for Systems Biomedicine, University of Luxembourg, Luxembourg City, Luxembourg, Pacific Northwest Diabetes Research, Seattle, Washington, United States of America

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  • Published: December 10, 2012
  • DOI: 10.1371/journal.pone.0051009

About the Authors

Kai Wang, Hong Li, Yue Yuan, Alton Etheridge, Yong Zhou, David Huang, David Galas
Institute for Systems Biology, Seattle, Washington, United States of America
Paul Wilmes, David Galas
Luxembourg Center for Systems Biomedicine, University of Luxembourg, Luxembourg City, Luxembourg
Alton Etheridge, David Huang, David Galas
Pacific Northwest Diabetes Research, Seattle, Washington, United States of America

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: KW HL PW DG. Performed the experiments: HL DH YY AE YZ. Analyzed the data: KW HL PW AE YZ DG. Contributed reagents/materials/analysis tools: HL PW. Wrote the paper: KW DG.