Advertisement
Research Article

Treponema pallidum Infection in the Wild Baboons of East Africa: Distribution and Genetic Characterization of the Strains Responsible

  • Kristin N. Harper mail,

    kh2383@columbia.edu

    Affiliation: Department of Environmental Health Sciences, Columbia University Medical Center, New York, New York, United States of America

    X
  • Robert D. Fyumagwa,

    Affiliation: Wildlife Veterinary Program, Tanzania Wildlife Research Institute, Arusha, Tanzania

    X
  • Richard Hoare,

    Affiliation: Wildlife Veterinary Program, Tanzania Wildlife Research Institute, Arusha, Tanzania

    X
  • Philemon N. Wambura,

    Affiliation: Department of Veterinary Microbiology and Parasitology, Faculty of Veterinary Medicine, Sokoine University of Agriculture, Morogoro, Tanzania

    X
  • Dorian H. Coppenhaver,

    Affiliation: Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, United States of America

    X
  • Robert M. Sapolsky,

    Affiliations: Biological Sciences, Stanford University, Stanford, California, United States of America, Institute of Primate Research, National Museums of Kenya, Nairobi, Kenya

    X
  • Susan C. Alberts,

    Affiliations: Institute of Primate Research, National Museums of Kenya, Nairobi, Kenya, Department of Biology, Duke University, Durham, North Carolina, United States of America

    X
  • Jenny Tung,

    Affiliations: Department of Evolutionary Anthropology, Duke University, Durham, North Carolina, United States of America, Population Research Institute, Duke University, Durham, North Carolina, United States of America

    X
  • Jeffrey Rogers,

    Affiliation: Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, United States of America

    X
  • Morris Kilewo,

    Affiliation: Department of Ecology, Tanzania National Parks, Arusha, Tanzania

    X
  • Emmanuel K. Batamuzi,

    Affiliation: Department of Veterinary Surgery and Theriogenology, Sokoine University of Agriculture, Morogoro, Tanzania

    X
  • Fabian H. Leendertz,

    Affiliation: Research Group Emerging Zoonoses, Robert Koch-Institute, Berlin, Germany

    X
  • George J. Armelagos,

    Affiliation: Department of Anthropology, Emory University, Atlanta, Georgia, United States of America

    X
  • Sascha Knauf

    Affiliation: Pathology Unit, German Primate Centre, Leibniz Institute for Primate Research, Göttingen, Germany

    X
  • Published: December 20, 2012
  • DOI: 10.1371/journal.pone.0050882

About the Authors

Kristin N. Harper
Department of Environmental Health Sciences, Columbia University Medical Center, New York, New York, United States of America
Robert D. Fyumagwa, Richard Hoare
Wildlife Veterinary Program, Tanzania Wildlife Research Institute, Arusha, Tanzania
Philemon N. Wambura
Department of Veterinary Microbiology and Parasitology, Faculty of Veterinary Medicine, Sokoine University of Agriculture, Morogoro, Tanzania
Dorian H. Coppenhaver
Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, United States of America
Robert M. Sapolsky
Biological Sciences, Stanford University, Stanford, California, United States of America
Robert M. Sapolsky, Susan C. Alberts
Institute of Primate Research, National Museums of Kenya, Nairobi, Kenya
Susan C. Alberts
Department of Biology, Duke University, Durham, North Carolina, United States of America
Jenny Tung
Department of Evolutionary Anthropology, Duke University, Durham, North Carolina, United States of America
Jenny Tung
Population Research Institute, Duke University, Durham, North Carolina, United States of America
Jeffrey Rogers
Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, United States of America
Morris Kilewo
Department of Ecology, Tanzania National Parks, Arusha, Tanzania
Emmanuel K. Batamuzi
Department of Veterinary Surgery and Theriogenology, Sokoine University of Agriculture, Morogoro, Tanzania
Fabian H. Leendertz
Research Group Emerging Zoonoses, Robert Koch-Institute, Berlin, Germany
George J. Armelagos
Department of Anthropology, Emory University, Atlanta, Georgia, United States of America
Sascha Knauf
Pathology Unit, German Primate Centre, Leibniz Institute for Primate Research, Göttingen, Germany

Corresponding Author

Email: kh2383@columbia.edu

Competing Interests

This project received support from the Scil Animal Care Company, Telinject Inc., and Translogistic Inc. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: KNH RDF RH SK GJA. Analyzed the data: KNH FHL SK GJA. Contributed reagents/materials/analysis tools: KNH FHL SK GJA. Wrote the paper: KNH RDF SK. Involved in collecting the samples: RDF RH PNW DHC RMS SCA JT JR MK EKB FHL SK. Carried out the serological and genetic analyses: KNH FHL SK GJA.