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Research Article

Plasmodium berghei Δp52&p36 Parasites Develop Independent of a Parasitophorous Vacuole Membrane in Huh-7 Liver Cells

  • Ivo H. J. Ploemen,

    Affiliation: Department of Medical Microbiology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands

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  • Huib J. Croes,

    Affiliation: Department of Cell Biology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands

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  • Geert-Jan J. van Gemert,

    Affiliation: Department of Medical Microbiology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands

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  • Mietske Wijers-Rouw,

    Affiliation: Department of Cell Biology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands

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  • Cornelus C. Hermsen,

    Affiliation: Department of Medical Microbiology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands

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  • Robert W. Sauerwein mail

    R.Sauerwein@mmb.umcn.nl

    Affiliation: Department of Medical Microbiology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands

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  • Published: December 05, 2012
  • DOI: 10.1371/journal.pone.0050772

About the Authors

Ivo H. J. Ploemen, Geert-Jan J. van Gemert, Cornelus C. Hermsen, Robert W. Sauerwein
Department of Medical Microbiology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
Huib J. Croes, Mietske Wijers-Rouw
Department of Cell Biology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands

Corresponding Author

Email: R.Sauerwein@mmb.umcn.nl

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: IHJP HJC. Performed the experiments: IHJP HJC MWR. Analyzed the data: IHJP. Contributed reagents/materials/analysis tools: HJC GJvG CCH MWR. Wrote the paper: IHJP RWS.