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Research Article

Titanium Dioxide (TiO2) Nanoparticles Preferentially Induce Cell Death in Transformed Cells in a Bak/Bax-Independent Fashion

  • Yanglong Zhu,

    Affiliation: Molecular Targets Program, James Graham Brown Cancer Center, Department of Medicine, Department of Pharmacology and Toxicology, University of Louisville, Louisville, Kentucky, United States of America

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  • John W. Eaton,

    Affiliation: Molecular Targets Program, James Graham Brown Cancer Center, Department of Medicine, Department of Pharmacology and Toxicology, University of Louisville, Louisville, Kentucky, United States of America

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  • Chi Li mail

    chi.li@louisville.edu

    Affiliation: Molecular Targets Program, James Graham Brown Cancer Center, Department of Medicine, Department of Pharmacology and Toxicology, University of Louisville, Louisville, Kentucky, United States of America

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  • Published: November 21, 2012
  • DOI: 10.1371/journal.pone.0050607

About the Authors

Yanglong Zhu, John W. Eaton, Chi Li
Molecular Targets Program, James Graham Brown Cancer Center, Department of Medicine, Department of Pharmacology and Toxicology, University of Louisville, Louisville, Kentucky, United States of America

Corresponding Author

Email: chi.li@louisville.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: YZ JWE CL. Performed the experiments: YZ. Analyzed the data: YZ JWE CL. Contributed reagents/materials/analysis tools: YZ. Wrote the paper: YZ JWE CL.