Protein Tyrosine Phosphatase µ (PTP µ or PTPRM), a Negative Regulator of Proliferation and Invasion of Breast Cancer Cells, Is Associated with Disease Prognosis

Ping-Hui Sun; Lin Ye; Malcolm D. Mason; Wen G. Jiang

doi:10.1371/journal.pone.0050183

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Open Access

Peer-reviewed

Research Article

Protein Tyrosine Phosphatase µ (PTP µ or PTPRM), a Negative Regulator of Proliferation and Invasion of Breast Cancer Cells, Is Associated with Disease Prognosis

Ping-Hui Sun ,

* E-mail: sunp2@cf.ac.uk

Affiliation Metastasis & Angiogenesis Research Group, Institute of Cancer and Genetics, Cardiff University School of Medicine, Cardiff, United Kingdom
⨯
Lin Ye,

Affiliation Metastasis & Angiogenesis Research Group, Institute of Cancer and Genetics, Cardiff University School of Medicine, Cardiff, United Kingdom
⨯
Malcolm D. Mason,

Affiliation Metastasis & Angiogenesis Research Group, Institute of Cancer and Genetics, Cardiff University School of Medicine, Cardiff, United Kingdom
⨯
Wen G. Jiang

Affiliation Metastasis & Angiogenesis Research Group, Institute of Cancer and Genetics, Cardiff University School of Medicine, Cardiff, United Kingdom
⨯

Protein Tyrosine Phosphatase µ (PTP µ or PTPRM), a Negative Regulator of Proliferation and Invasion of Breast Cancer Cells, Is Associated with Disease Prognosis

Ping-Hui Sun,
Lin Ye,
Malcolm D. Mason,
Wen G. Jiang

Published: November 20, 2012
https://doi.org/10.1371/journal.pone.0050183

About the Authors

Ping-Hui Sun

* E-mail: sunp2@cf.ac.uk

Affiliation Metastasis & Angiogenesis Research Group, Institute of Cancer and Genetics, Cardiff University School of Medicine, Cardiff, United Kingdom

Lin Ye

Affiliation Metastasis & Angiogenesis Research Group, Institute of Cancer and Genetics, Cardiff University School of Medicine, Cardiff, United Kingdom

Malcolm D. Mason

Affiliation Metastasis & Angiogenesis Research Group, Institute of Cancer and Genetics, Cardiff University School of Medicine, Cardiff, United Kingdom

Wen G. Jiang

Affiliation Metastasis & Angiogenesis Research Group, Institute of Cancer and Genetics, Cardiff University School of Medicine, Cardiff, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: PS LY MM WJ. Performed the experiments: PS. Analyzed the data: PS LY. Contributed reagents/materials/analysis tools: LY WJ. Wrote the paper: PS LY.

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Breast cancer
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Differentiated tumors
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Tyrosine
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Lung and intrathoracic tumors
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Cancer cell migration
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Prognosis
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Thyroid carcinoma
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Cancer treatment
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