About the Authors

Ji Chen

Contributed equally to this work with: Ji Chen, Jianying Chen, Shuzhen Chen

Affiliations Department of Pharmacology & Toxicology, Boonshoft School of Medicine, Wright State University, Dayton, Ohio, United States of America, Clinical Research Center and Department of Neurology, the Affiliated Hospital of Guangdong Medical College, Zhanjiang, Guangdong, People’s Republic of China

Jianying Chen

Contributed equally to this work with: Ji Chen, Jianying Chen, Shuzhen Chen

Affiliation Clinical Research Center and Department of Neurology, the Affiliated Hospital of Guangdong Medical College, Zhanjiang, Guangdong, People’s Republic of China

Shuzhen Chen

Contributed equally to this work with: Ji Chen, Jianying Chen, Shuzhen Chen

Affiliation Department of Pharmacology & Toxicology, Boonshoft School of Medicine, Wright State University, Dayton, Ohio, United States of America

Cheng Zhang

Affiliation Department of Pharmacology & Toxicology, Boonshoft School of Medicine, Wright State University, Dayton, Ohio, United States of America

Liangqing Zhang

Affiliation Clinical Research Center and Department of Neurology, the Affiliated Hospital of Guangdong Medical College, Zhanjiang, Guangdong, People’s Republic of China

Xiang Xiao

Affiliation Department of Pharmacology & Toxicology, Boonshoft School of Medicine, Wright State University, Dayton, Ohio, United States of America

Avik Das

Affiliation Department of Pharmacology & Toxicology, Boonshoft School of Medicine, Wright State University, Dayton, Ohio, United States of America

Yuhui Zhao

Affiliations Department of Pharmacology & Toxicology, Boonshoft School of Medicine, Wright State University, Dayton, Ohio, United States of America, Department of Neurology, the First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, People’s Republic of China

Bin Yuan

Affiliations Department of Pharmacology & Toxicology, Boonshoft School of Medicine, Wright State University, Dayton, Ohio, United States of America, Clinical Research Center and Department of Neurology, the Affiliated Hospital of Guangdong Medical College, Zhanjiang, Guangdong, People’s Republic of China

Mariana Morris

Affiliation Department of Pharmacology & Toxicology, Boonshoft School of Medicine, Wright State University, Dayton, Ohio, United States of America

Bin Zhao

These authors also contributed equally to this work.

Affiliation Clinical Research Center and Department of Neurology, the Affiliated Hospital of Guangdong Medical College, Zhanjiang, Guangdong, People’s Republic of China

Yanfang Chen

yanfang.chen@wright.edu

These authors also contributed equally to this work.

Affiliations Department of Pharmacology & Toxicology, Boonshoft School of Medicine, Wright State University, Dayton, Ohio, United States of America, Clinical Research Center and Department of Neurology, the Affiliated Hospital of Guangdong Medical College, Zhanjiang, Guangdong, People’s Republic of China

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: Ji Chen Jianying Chen BZ YC. Performed the experiments: Ji Chen Jianying Chen SC CZ XX LZ BY AD YZ. Analyzed the data: Ji Chen Jianying Chen SC CZ XX LZ AD YZ. Contributed reagents/materials/analysis tools: MM. Wrote the paper: Ji Chen Jianying Chen BZ YC. Revised the manuscript: Ji Chen MM YC.