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Research Article

Lipocalin 2 Regulates Inflammation during Pulmonary Mycobacterial Infections

  • Lokesh Guglani equal contributor,

    equal contributor Contributed equally to this work with: Lokesh Guglani, Radha Gopal

    Affiliation: Division of Pulmonary Medicine, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America

    X
  • Radha Gopal equal contributor,

    equal contributor Contributed equally to this work with: Lokesh Guglani, Radha Gopal

    Affiliation: Division of Infectious Diseases, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America

    X
  • Javier Rangel-Moreno,

    Affiliation: Division of Allergy, Immunology and Rheumatology, Department of Medicine, University of Rochester Medical Center, Rochester, New York, United States of America

    X
  • Beth Fallert Junecko,

    Affiliation: Department of Infectious Diseases and Microbiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

    X
  • Yinyao Lin,

    Affiliation: Division of Infectious Diseases, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America

    X
  • Thorsten Berger,

    Affiliation: The Campbell Family Institute for Breast Cancer Research and the Ontario Cancer Institute, University Health Network, Toronto, Canada

    X
  • Tak W. Mak,

    Affiliation: The Campbell Family Institute for Breast Cancer Research and the Ontario Cancer Institute, University Health Network, Toronto, Canada

    X
  • John F. Alcorn,

    Affiliation: Division of Pulmonary Medicine, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America

    X
  • Troy D. Randall,

    Affiliation: Division of Allergy, Immunology and Rheumatology, Department of Medicine, University of Rochester Medical Center, Rochester, New York, United States of America

    X
  • Todd A. Reinhart,

    Affiliation: Department of Infectious Diseases and Microbiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

    X
  • Yvonne R. Chan,

    Affiliation: Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America

    X
  • Shabaana A. Khader mail

    Shabaana.Khader@chp.edu

    Affiliation: Division of Infectious Diseases, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America

    X
  • Published: November 20, 2012
  • DOI: 10.1371/journal.pone.0050052

About the Authors

Lokesh Guglani, John F. Alcorn
Division of Pulmonary Medicine, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
Radha Gopal, Yinyao Lin, Shabaana A. Khader
Division of Infectious Diseases, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
Javier Rangel-Moreno, Troy D. Randall
Division of Allergy, Immunology and Rheumatology, Department of Medicine, University of Rochester Medical Center, Rochester, New York, United States of America
Beth Fallert Junecko, Todd A. Reinhart
Department of Infectious Diseases and Microbiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
Thorsten Berger, Tak W. Mak
The Campbell Family Institute for Breast Cancer Research and the Ontario Cancer Institute, University Health Network, Toronto, Canada
Yvonne R. Chan
Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America

Corresponding Author

Email: Shabaana.Khader@chp.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: LG RG YRC SAK. Performed the experiments: LG RG JRM BFJ YL SAK. Analyzed the data: LG RG JRM YL. Contributed reagents/materials/analysis tools: TB TWM JFA TDR TAR YRC. Wrote the paper: LG RG SAK.