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Research Article

Function Annotation of Hepatic Retinoid x Receptor α Based on Genome-Wide DNA Binding and Transcriptome Profiling

  • Qi Zhan,

    Affiliation: Department of Gastroenterology Hepatology, Guangzhou First Municipal People's Hospital, Guangzhou Medical College, Guangzhou, Guangdong Province, China

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  • Yaping Fang,

    Affiliation: Applied Bioinformatics Laboratory, University of Kansas, Lawrence, Kansas, United States of America

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  • Yuqi He,

    Affiliation: Department of Medical Pathology and Laboratory Medicine, University of California Davis, Davis Health Systems, Sacramento, California, United States of America

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  • Hui-Xin Liu,

    Affiliation: Department of Medical Pathology and Laboratory Medicine, University of California Davis, Davis Health Systems, Sacramento, California, United States of America

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  • Jianwen Fang,

    Affiliation: Applied Bioinformatics Laboratory, University of Kansas, Lawrence, Kansas, United States of America

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  • Yu-Jui Yvonne Wan mail

    yjywan@ucdavis.edu

    Affiliations: Department of Gastroenterology Hepatology, Guangzhou First Municipal People's Hospital, Guangzhou Medical College, Guangzhou, Guangdong Province, China, Department of Medical Pathology and Laboratory Medicine, University of California Davis, Davis Health Systems, Sacramento, California, United States of America

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  • Published: November 15, 2012
  • DOI: 10.1371/journal.pone.0050013

About the Authors

Qi Zhan, Yu-Jui Yvonne Wan
Department of Gastroenterology Hepatology, Guangzhou First Municipal People's Hospital, Guangzhou Medical College, Guangzhou, Guangdong Province, China
Yuqi He, Hui-Xin Liu, Yu-Jui Yvonne Wan
Department of Medical Pathology and Laboratory Medicine, University of California Davis, Davis Health Systems, Sacramento, California, United States of America
Yaping Fang, Jianwen Fang
Applied Bioinformatics Laboratory, University of Kansas, Lawrence, Kansas, United States of America

Corresponding Author

Email: yjywan@ucdavis.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: QZ YYW. Performed the experiments: QZ YH HL. Analyzed the data: QZ YF YH JF. Contributed reagents/materials/analysis tools: QZ YF YH. Wrote the paper: QZ YYW.