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Research Article

A Simplified Method for the Efficient Refolding and Purification of Recombinant Human GM-CSF

  • Christy A. Thomson,

    Affiliation: The Biomedical Research Centre, University of British Columbia, Vancouver, British Columbia, Canada

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  • Melanie Olson,

    Affiliation: The Biomedical Research Centre, University of British Columbia, Vancouver, British Columbia, Canada

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  • Linda M. Jackson,

    Affiliation: The Biomedical Research Centre, University of British Columbia, Vancouver, British Columbia, Canada

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  • John W. Schrader mail

    john@brc.ubc.ca

    Affiliation: The Biomedical Research Centre, University of British Columbia, Vancouver, British Columbia, Canada

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  • Published: November 14, 2012
  • DOI: 10.1371/journal.pone.0049891

About the Authors

Christy A. Thomson, Melanie Olson, Linda M. Jackson, John W. Schrader
The Biomedical Research Centre, University of British Columbia, Vancouver, British Columbia, Canada

Corresponding Author

Email: john@brc.ubc.ca

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: CAT JWS. Performed the experiments: CAT MO LMJ. Analyzed the data: CAT MO LMJ. Contributed reagents/materials/analysis tools: JWS. Wrote the paper: CAT.