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Research Article

Drug-Eluting Fibers for HIV-1 Inhibition and Contraception

  • Cameron Ball,

    Affiliation: Department of Bioengineering, University of Washington, Seattle, Washington, United States of America

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  • Emily Krogstad,

    Affiliation: Department of Bioengineering, University of Washington, Seattle, Washington, United States of America

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  • Thanyanan Chaowanachan,

    Affiliation: Department of Bioengineering, University of Washington, Seattle, Washington, United States of America

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  • Kim A. Woodrow mail

    woodrow@u.washington.edu

    Affiliation: Department of Bioengineering, University of Washington, Seattle, Washington, United States of America

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  • Published: November 28, 2012
  • DOI: 10.1371/journal.pone.0049792

About the Authors

Cameron Ball, Emily Krogstad, Thanyanan Chaowanachan, Kim A. Woodrow
Department of Bioengineering, University of Washington, Seattle, Washington, United States of America

Corresponding Author

Email: woodrow@u.washington.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: CB EK TC KAW. Performed the experiments: CB EK TC. Analyzed the data: CB EK TC. Contributed reagents/materials/analysis tools: KAW. Wrote the paper: CB EK TC KAW. Conceived of using electrospun fibers for topical drug delivery: KAW. Conceived of the electrospinning apparatus and collection mandrel: CB EK KAW. Build the electrospinning apparatus: CB. Performed all the fiber experiments including the mouse studies, and contributed equally to the data analysis: CB EK. Performed and analyzed the explant tissue studies: TC.