About the Authors
- Hugo Geerts
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* E-mail: Hugo-Geerts@In-Silico-Biosciences.com
Affiliation In Silico Biosciences, Berwyn, Pennsylvania, United States of America
- Athan Spiros
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Affiliation In Silico Biosciences, Berwyn, Pennsylvania, United States of America
- Patrick Roberts
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Affiliation In Silico Biosciences, Berwyn, Pennsylvania, United States of America
- Roy Twyman
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Affiliation Johnson & Johnson Pharmaceutical Research and Development, Central Nervous System Development, Titusville, New Jersey, United States of America
- Larry Alphs
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Affiliation Janssen Scientific Affairs, LLC, Titusville, New Jersey, United States of America
- Anthony A. Grace
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Affiliation Department of Neuroscience, Psychiatry, and Psychology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
Competing Interests
The authors have read the journal's policy and have the following conflicts: H.G., A.S. and P.R. are employees of In Silico Biosciences, the funder of this study. R.T. is an employee of J&J, L.A. is an employee of Janssen Scientific Affairs and A.G. is a consultant for J&J and Lundbeck and has financial relationships with Johnson & Johnson, Lundbeck, Pfizer, GSK, Puretech Ventures, Merck, Takeda, and Dainippon Sumimoto. The computer-based platform is covered by the recently granted US patent “Method and apparatus for computer modeling of the interaction between cortical and subcortical areas in the human brain” - Hugo Geerts, Athan Spiros. PCT/US2006/043887, US patent 8,150,629 B2, granted on April 30, 2012.” A patent for the composition of matter for JNJ37822681 has been applied for. There are no further patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: HG AS PR. Performed the experiments: HG. Analyzed the data: HG AS PR RT LA. Contributed reagents/materials/analysis tools: HG AS PR RT LA AG. Wrote the paper: HG AG.