Advertisement
Research Article

The Human Cytomegalovirus DNA Polymerase Processivity Factor UL44 Is Modified by SUMO in a DNA-Dependent Manner

  • Elisa Sinigalia equal contributor,

    equal contributor Contributed equally to this work with: Elisa Sinigalia, Gualtiero Alvisi, Chiara V. Segré, Beatrice Mercorelli

    Affiliation: Department of Molecular Medicine, University of Padua, Padua, Italy

    X
  • Gualtiero Alvisi equal contributor,

    equal contributor Contributed equally to this work with: Elisa Sinigalia, Gualtiero Alvisi, Chiara V. Segré, Beatrice Mercorelli

    Affiliations: Department of Molecular Medicine, University of Padua, Padua, Italy, Department of Hematology and Medical Oncology Seragnoli, University of Bologna, Bologna, Italy, Department of Infectious Diseases, Molecular Virology, University of Heidelberg, Heidelberg, Germany

    X
  • Chiara V. Segré equal contributor,

    equal contributor Contributed equally to this work with: Elisa Sinigalia, Gualtiero Alvisi, Chiara V. Segré, Beatrice Mercorelli

    Affiliation: European Institute of Oncology, Milan, Italy

    X
  • Beatrice Mercorelli equal contributor,

    equal contributor Contributed equally to this work with: Elisa Sinigalia, Gualtiero Alvisi, Chiara V. Segré, Beatrice Mercorelli

    Affiliation: Department of Molecular Medicine, University of Padua, Padua, Italy

    X
  • Giulia Muratore,

    Affiliation: Department of Molecular Medicine, University of Padua, Padua, Italy

    X
  • Michael Winkler,

    Affiliation: Leibniz-Institut für Primatenforschung, Goettingen, Germany

    X
  • He-Hsuan Hsiao,

    Affiliation: Bioanalytical Mass Spectrometry Group, Max Planck Institute for Biophysical Chemistry, Goettingen, Germany

    X
  • Henning Urlaub,

    Affiliations: Bioanalytical Mass Spectrometry Group, Max Planck Institute for Biophysical Chemistry, Goettingen, Germany, Bioanalytics, Department of Clinical Chemistry, University Medical Center, Goettingen, Germany

    X
  • Alessandro Ripalti,

    Affiliation: Azienda Ospedaliero-Universitaria di Bologna, Policlinico S. Orsola-Malpighi, Bologna, Italy

    X
  • Susanna Chiocca,

    Affiliation: European Institute of Oncology, Milan, Italy

    X
  • Giorgio Palù mail,

    giorgio.palu@unipd.it (GP); arianna.loregian@unipd.it (AL)

    Affiliation: Department of Molecular Medicine, University of Padua, Padua, Italy

    X
  • Arianna Loregian mail

    giorgio.palu@unipd.it (GP); arianna.loregian@unipd.it (AL)

    Affiliation: Department of Molecular Medicine, University of Padua, Padua, Italy

    X
  • Published: November 15, 2012
  • DOI: 10.1371/journal.pone.0049630

About the Authors

Elisa Sinigalia, Gualtiero Alvisi, Beatrice Mercorelli, Giulia Muratore, Giorgio Palù, Arianna Loregian
Department of Molecular Medicine, University of Padua, Padua, Italy
Gualtiero Alvisi
Department of Hematology and Medical Oncology Seragnoli, University of Bologna, Bologna, Italy
Gualtiero Alvisi
Department of Infectious Diseases, Molecular Virology, University of Heidelberg, Heidelberg, Germany
Chiara V. Segré, Susanna Chiocca
European Institute of Oncology, Milan, Italy
Michael Winkler
Leibniz-Institut für Primatenforschung, Goettingen, Germany
He-Hsuan Hsiao, Henning Urlaub
Bioanalytical Mass Spectrometry Group, Max Planck Institute for Biophysical Chemistry, Goettingen, Germany
Henning Urlaub
Bioanalytics, Department of Clinical Chemistry, University Medical Center, Goettingen, Germany
Alessandro Ripalti
Azienda Ospedaliero-Universitaria di Bologna, Policlinico S. Orsola-Malpighi, Bologna, Italy

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: ES GA CVS BM MW HU AR SC GP AL. Performed the experiments: ES GA CVS BM GM MW H-HH HU AL. Analyzed the data: ES GA CVS BM MW H-HH HU AR SC GP AL. Wrote the paper: ES GA BM HU SC GP AL.