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Research Article

The Sec1/Munc18 Protein Vps45 Regulates Cellular Levels of Its SNARE Binding Partners Tlg2 and Snc2 in Saccharomyces cerevisiae

  • Scott G. Shanks,

    Affiliation: Henry Wellcome Laboratory of Cell Biology, Institute of Molecular, Cell & Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom

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  • Lindsay N. Carpp,

    Affiliation: Henry Wellcome Laboratory of Cell Biology, Institute of Molecular, Cell & Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom

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  • Marion S. Struthers,

    Affiliation: Henry Wellcome Laboratory of Cell Biology, Institute of Molecular, Cell & Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom

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  • Rebecca K. McCann,

    Affiliation: Henry Wellcome Laboratory of Cell Biology, Institute of Molecular, Cell & Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom

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  • Nia J. Bryant mail

    nia.bryant@glasgow.ac.uk

    Affiliation: Henry Wellcome Laboratory of Cell Biology, Institute of Molecular, Cell & Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom

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  • Published: November 14, 2012
  • DOI: 10.1371/journal.pone.0049628

About the Authors

Scott G. Shanks, Lindsay N. Carpp, Marion S. Struthers, Rebecca K. McCann, Nia J. Bryant
Henry Wellcome Laboratory of Cell Biology, Institute of Molecular, Cell & Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom

Corresponding Author

Email: nia.bryant@glasgow.ac.uk

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: NJB SGS. Performed the experiments: SGS LNC MSS. Analyzed the data: NJB SGS. Contributed reagents/materials/analysis tools: SGS LNC RKM MSS. Wrote the paper: NJB SGS.