About the Authors

Natalia N. Singh

Contributed equally to this work with: Natalia N. Singh, Joonbae Seo

Affiliation Department of Biomedical Sciences, Iowa State University, Ames, Iowa, United States of America

Joonbae Seo

Contributed equally to this work with: Natalia N. Singh, Joonbae Seo

Affiliation Department of Biomedical Sciences, Iowa State University, Ames, Iowa, United States of America

Sarah J. Rahn

Affiliation Department of Biomedical Sciences, Iowa State University, Ames, Iowa, United States of America

Ravindra N. Singh

singhr@iastate.edu

Affiliation Department of Biomedical Sciences, Iowa State University, Ames, Iowa, United States of America

Competing Interests

The authors have the following interests. Iowa State University holds the intellectual property rights on ASO (3UP8) described in this study (Patent# US 20110269820 A1). Therefore, authors (RNS and NNS) and Iowa State University could potentially benefit from any future commercial exploitation of the above-mentioned ASO. There are no further patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: RNS NNS JS SJR. Performed the experiments: NNS JS SJR. Analyzed the data: RNS NNS JS SJR. Contributed reagents/materials/analysis tools: RNS. Wrote the paper: RNS NNS.